Prss2
Gene Detail

Symbol Name ID

Prss2 protease, serine, 2 MGI:102759

Synonyms

Ta, Tesp4, Try2, TRY8, TRYP

Feature Type

protein coding gene

Genetic Map

Chromosome 6

19.67 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr6:41521787-41525079 bp, + strand From VEGA annotation of GRCm38   3293 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:122141  Vertebrate Homology Class
1 mouse; 1 rat; 2 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: trypsin
Gene Tree: Prss2

Alleles and phenotypes

All alleles(3) : Targeted(3)

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	digestion, response to caffeine, ...
Component	extracellular space
Function	catalytic activity, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
cDNA source data(569)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(572) Genomic(1) cDNA(569) Other(2)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000026925 (Evidence)
Ensembl Gene Model	ENSMUSG00000057163 (Evidence)
Entrez Gene	22072 (Evidence)
UniGene	276926
DFCI	TC1573999, TC1701640
NIA Mouse Gene Index	U367048
EC	3.4.21.4
Consensus CDS Project	CCDS20050.1
International Mouse Knockout Project Status	Prss2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000026925	VEGA Gene Model | MGI Sequence Detail	3293	C57BL/6J
transcript	OTTMUST00000066577	VEGA | MGI Sequence Detail	815	Not Applicable
polypeptide	OTTMUSP00000033386	VEGA | MGI Sequence Detail	246	Not Applicable

All sequences(24) RefSeq(3) UniProt(2)

Polymorphisms

SNPs(106 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR009003	Peptidase cysteine/serine, trypsin-like
InterPro	IPR001314	Peptidase S1A, chymotrypsin-type
InterPro	IPR001254	Peptidase S1/S6, chymotrypsin/Hap
InterPro	IPR018114	Peptidase S1/S6, chymotrypsin/Hap, active site
Protein Ontology	PR:000027796	trypsin-2

References

(Earliest) J:8507 Stevenson BJ, et al., Sequence organisation and transcriptional regulation of the mouse elastase II and trypsin genes. Nucleic Acids Res. 1986 Nov 11;14(21):8307-30
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)

Other accession IDs

MGD-MRK-19664