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Prss3
Gene Detail
Symbol

Name
ID
Prss3
protease, serine 3
MGI:102758
Synonyms
mesotrypsin, MTG, Tb, Try3, TRY4
Feature Type
protein coding gene
Genetic Map
Chromosome 6
19.50 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr6:41373814-41377678 bp, - strand
From VEGA annotation of GRCm38

  3865 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:88408  Vertebrate Homology Class
4 mouse; 5 rat

Protein SuperFamily: trypsin
Gene Tree: Prss3

Mutations,
alleles, and
phenotypes
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process digestion, proteolysis
Component extracellular space
Function serine-type endopeptidase activity
External Resources: FuncBase
Expression
cDNA source data(46)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(47) Genomic(1) cDNA(46)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000051420 (Evidence)
Ensembl Gene ModelENSMUSG00000071519 (Evidence)
Entrez Gene22073 (Evidence)
UniGene425318
DoTSDT.492411, DT.101715061
Consensus CDS ProjectCCDS20047.1
International Mouse Knockout Project StatusPrss3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000051420 VEGA Gene Model | MGI Sequence Detail 3865 C57BL/6J ±  kb
transcript OTTMUST00000129977 VEGA | MGI Sequence Detail 822 Not Applicable 
polypeptide OTTMUSP00000069739 VEGA | MGI Sequence Detail 246 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(3) UniProt(4)
Polymorphisms
SNPs within 2kb(4 from dbSNP Build 137)    SNPs within 2kb including multiple locations(6)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
References
(Earliest) J:8507 Stevenson BJ, et al., Sequence organisation and transcriptional regulation of the mouse elastase II and trypsin genes. Nucleic Acids Res. 1986 Nov 11;14(21):8307-30
(Latest) J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
All references(20)
Other
accession IDs
MGD-MRK-19663

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/24/2015
MGI 5.21
The Jackson Laboratory