Prss3
Gene Detail

Symbol Name ID

Prss3 protease, serine, 3 MGI:102758

Synonyms

mesotrypsin, MTG, Tb, Try3, TRY4

Feature Type

protein coding gene

Genetic Map

Chromosome 6

19.50 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr6:41373759-41377613 bp, - strand From NCBI annotation of GRCm38   3855 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:88408  Vertebrate Homology Class
1 human; 4 mouse; 3 rat; 1 chimpanzee; 1 rhesus macaque

Protein SuperFamily: trypsin
Gene Tree: Prss3

Human homologs

Human Homolog		PRSS3, protease, serine, 3
NCBI Gene ID		5646
neXtProt AC		NX_P35030
Human Synonyms		MTG, PRSS4, T9, TRY3, TRY4
Human Chr (Location)		9p11.2; chr9:33750464-33799229 (+)  GRCh37.p10

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	metabolic process, proteolysis
Component	extracellular space
Function	calcium ion binding, hydrolase activity, ...

External Resources: FuncBase

Expression

cDNA source data(45)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(46) Genomic(1) cDNA(45)
Microarray probesets(2)

Other database links

Ensembl Gene Model	ENSMUSG00000071519 (Evidence)
Entrez Gene	22073 (Evidence)
UniGene	425318
DoTS	DT.101715061, DT.492411
Consensus CDS Project	CCDS20047.1
International Mouse Knockout Project Status	Prss3

Sequences

Length	Strain/Species
genomic	22073	NCBI Gene Model | MGI Sequence Detail	3855	C57BL/6J
transcript	NM_011645	RefSeq | MGI Sequence Detail	812	Not Specified
polypeptide	NP_035775	RefSeq | MGI Sequence Detail	246	Not Specified

All sequences(18) RefSeq(3) UniProt(4)

Protein-related information

Resource	ID	Description
InterPro	IPR001254	Peptidase S1
InterPro	IPR001314	Peptidase S1A, chymotrypsin-type
InterPro	IPR018114	Peptidase S1, trypsin family, active site
InterPro	IPR009003	Trypsin-like cysteine/serine peptidase domain

References

(Earliest) J:8507 Stevenson BJ, et al., Sequence organisation and transcriptional regulation of the mouse elastase II and trypsin genes. Nucleic Acids Res. 1986 Nov 11;14(21):8307-30
(Latest) J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
All references(20)

Other accession IDs

MGD-MRK-19663