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Try4 Gene Detail
Summary
  • Symbol
    Try4
  • Name
    trypsin 4
  • Synonyms
    0910001B19Rik, Td
  • Feature Type
    protein coding gene
  • IDs
    MGI:102757
    NCBI Gene: 22074
  • Gene Overview
    MyGene.info: PRSS3
Location & Maps
more
  • Sequence Map
    Chr6:41302269-41305532 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3264 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    PRSS3, protease, serine 3
  • Vertebrate Orthologs
    6
  • Human Ortholog
    PRSS3, protease, serine 3
    Orthology source: HomoloGene
  • Synonyms
    MTG, PRSS4, T9, TRY3, TRY4
  • Links
    NCBI Gene ID: 5646
    neXtProt AC: NX_P35030

  • Chr Location
    9p11.2; chr9:33750466-33799231 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026910 VEGA Gene Model | MGI Sequence Detail 3264 C57BL/6J ±  kb
transcript OTTMUST00000066552 VEGA | MGI Sequence Detail 801 Not Applicable  
polypeptide OTTMUSP00000033368 VEGA | MGI Sequence Detail 246 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    29 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR001314 Peptidase S1A, chymotrypsin family
    IPR009003 Peptidase S1, PA clan
    IPR001254 Serine proteases, trypsin domain
    IPR018114 Serine proteases, trypsin family, histidine active site
    IPR033116 Serine proteases, trypsin family, serine active site
Molecular
Reagents
less
  • All nucleic 443
    Genomic 2
    cDNA 441

    Microarray probesets 1
Other
Accession IDs
less
MGD-MRK-19662, MGI:1913350
References
more
  • Summaries
    All 20
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:8507 Stevenson BJ, et al., Sequence organisation and transcriptional regulation of the mouse elastase II and trypsin genes. Nucleic Acids Res. 1986 Nov 11;14(21):8307-30
  • Latest
    J:201436 Chang I, et al., Endothelin-2 deficiency causes growth retardation, hypothermia, and emphysema in mice. J Clin Invest. 2013 Jun 3;123(6):2643-53

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory