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Try5
Gene Detail
 Symbol
Name
ID
Try5
trypsin 5
MGI:102756
Synonyms 1810049H19Rik, Tc
Feature Type protein coding gene
Genetic Map
Chromosome 6
19.43 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr6:41311233-41316841 bp, - strand
From VEGA annotation of GRCm38

  5609 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:106639  Vertebrate Homology Class
1 human; 2 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque

Protein SuperFamily: trypsin
Gene Tree: Try5

Human
homologs
Human Homolog PRSS3, protease, serine, 3
NCBI Gene ID 5646
neXtProt AC  NX_P35030
Human Synonyms  MTG, PRSS4, T9, TRY3, TRY4
Human Chr (Location)  9p11.2; chr9:33750466-33799231 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from APF )
Interactions
Try5 interacts with 5 markers (Mir325, Mir455, Mir671, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process proteolysis
Component extracellular space, extracellular vesicular exosome
Function calcium ion binding, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (10)    Tissues (1)    Images (10)
Theiler Stages: 23
Assay TypeResults
RNA in situ 10
cDNA source data(418)
External Resources: Expression Atlas
Molecular
reagents
All nucleic(419) Genomic(1) cDNA(418)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000026909 (Evidence)
Ensembl Gene ModelENSMUSG00000036938 (Evidence)
Entrez Gene103964 (Evidence)
UniGene333022
Consensus CDS ProjectCCDS20045.1
International Mouse Knockout Project StatusTry5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026909 VEGA Gene Model | MGI Sequence Detail 5609 C57BL/6J ±  kb
transcript OTTMUST00000066551 VEGA | MGI Sequence Detail 801 Not Applicable 
polypeptide OTTMUSP00000033367 VEGA | MGI Sequence Detail 246 Not Applicable 

For the selected sequences
All sequences(27) RefSeq(3) UniProt(3)
Polymorphisms SNPs within 2kb(44 from dbSNP Build 137)    SNPs within 2kb including multiple locations(52)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
References (Earliest) J:8507 Stevenson BJ, et al., Sequence organisation and transcriptional regulation of the mouse elastase II and trypsin genes. Nucleic Acids Res. 1986 Nov 11;14(21):8307-30
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(20)
Other
accession IDs
MGD-MRK-19661, MGI:3045752

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory