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Nelfe Gene Detail
Summary
  • Symbol
    Nelfe
  • Name
    negative elongation factor complex member E, Rdbp
  • Synonyms
    NELF-E, Rdbp
  • Feature Type
    protein coding gene
  • IDs
    MGI:102744
    NCBI Gene: 27632
  • Gene Overview
    MyGene.info: NELFE
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:34850391-34856372 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 18.40 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102744
protein coding gene Chr17:34850391-34856372 (.)
129S1/SvImJ MGP_129S1SvImJ_G0023592
protein coding gene Chr17:34962208-34968189 (+)
A/J MGP_AJ_G0023554
protein coding gene Chr17:33820576-33826580 (+)
AKR/J MGP_AKRJ_G0023520
protein coding gene Chr17:34279447-34285452 (+)
BALB/cJ MGP_BALBcJ_G0023559
protein coding gene Chr17:33950888-33956892 (+)
C3H/HeJ MGP_C3HHeJ_G0023319
protein coding gene Chr17:34678818-34685690 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023999
protein coding gene Chr17:36299518-36305499 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021478
protein coding gene Chr17:31585054-31591267 (+)
CAST/EiJ MGP_CASTEiJ_G0022817
protein coding gene Chr17:34674564-34680563 (+)
CBA/J MGP_CBAJ_G0023297
protein coding gene Chr17:37811066-37817071 (+)
DBA/2J MGP_DBA2J_G0023425
protein coding gene Chr17:33134932-33140936 (+)
FVB/NJ MGP_FVBNJ_G0023392
protein coding gene Chr17:32965180-32971184 (+)
LP/J MGP_LPJ_G0023502
protein coding gene Chr17:35273064-35279045 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023415
protein coding gene Chr17:36739818-36745827 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024041
protein coding gene Chr17:34509351-34515333 (+)
PWK/PhJ MGP_PWKPhJ_G0022566
protein coding gene Chr17:31964508-31970590 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022383
protein coding gene Chr17:32510528-32516523 (+)
WSB/EiJ MGP_WSBEiJ_G0022879
protein coding gene Chr17:34618081-34624072 (+)



Homology
more
  • Human Ortholog
    NELFE, negative elongation factor complex member E
  • Vertebrate Orthologs
    6
  • Human Ortholog
    NELFE, negative elongation factor complex member E
    Orthology source: HomoloGene, HGNC
  • Synonyms
    D6S45, NELF-E, RD, RDBP, RDP
  • Links
    NCBI Gene ID: 7936
    neXtProt AC: NX_P18615
    UniProt: P18615

  • Chr Location
    6p21.33; chr6:31952087-31959087 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 27632 NCBI Gene Model | MGI Sequence Detail 5982 C57BL/6J ±  kb
transcript NM_001045864 RefSeq | MGI Sequence Detail 1621 C57BL/6  
polypeptide P19426 UniProt | EBI | MGI Sequence Detail 375 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    Genomic 5
    cDNA 12
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-19649
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:9107 Levi-Strauss M, et al., A previously undetected MHC gene with an unusual periodic structure. Science. 1988 Apr 8;240(4849):201-4
  • Latest
    J:233096 Childress P, et al., Genome-Wide Mapping and Interrogation of the Nmp4 Antianabolic Bone Axis. Mol Endocrinol. 2015 Sep;29(9):1269-85

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory