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Crybb3
Gene Detail
Symbol

Name
ID
Crybb3
crystallin, beta B3
MGI:102717
Feature Type
protein coding gene
Genetic Map
Chromosome 5
55.38 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr5:113075839-113081584 bp, - strand
From VEGA annotation of GRCm38

  5746 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3008  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CRYBB3
Protein SuperFamily: beta/gamma crystallins
Gene Tree: Crybb3

Human
homologs
CRYBB3, crystallin, beta B3
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 1417
neXtProt AC: NX_P26998

Human Synonyms: CATCN2, CRYB3, CTRCT22

Human Chr (Location): 22q11.23; chr22:25198686-25207363 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human CRYBB3

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Crybb3 interacts with 6 markers (Mir27a, Mir137, Mir325, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (1 annotations)
Function structural constituent of eye lens
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (18)    Tissues (2)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 18
cDNA source data(3)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase crybb3 ; ZFIN crybb3    NEW 
Molecular
reagents
All nucleic(5) cDNA(3) Primer pair(1) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000026830 (Evidence)
Ensembl Gene Model ENSMUSG00000029352 (Evidence)
Entrez Gene 12962 (Evidence)
DFCI TC1590478, TC1573737
DoTS DT.99851511, DT.91415312, DT.102535255, DT.101390871
NIA Mouse Gene Index U026585
Consensus CDS Project CCDS19547.1
International Mouse Phenotyping Consortium Status Crybb3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026830 VEGA Gene Model | MGI Sequence Detail 5746 C57BL/6J ±  kb
transcript OTTMUST00000066357 VEGA | MGI Sequence Detail 816 Not Applicable 
polypeptide OTTMUSP00000033245 VEGA | MGI Sequence Detail 211 Not Applicable 

For the selected sequences
All sequences(68) RefSeq(8) UniProt(5)
Polymorphisms
RFLP(1) : SNPs within 2kb(66 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001064 Beta/gamma crystallin
InterPro IPR011024 Gamma-crystallin-related
Protein Ontology PR:000005913 beta-crystallin B3
References
(Earliest) J:23156 Hulsebos TJ, et al., The beta crystallin genes on human chromosome 22 define a new region of homology with mouse chromosome 5. Genomics. 1995 Jan 20;25(2):574-6
(Latest) J:178731 Xie Q, et al., The Orchestration of Mammalian Tissue Morphogenesis through a Series of Coherent Feed-forward Loops. J Biol Chem. 2011 Dec 16;286(50):43259-71
All references(33)
Other
accession IDs
MGD-MRK-19621, MGI:2140996

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory