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Crybb3 Gene Detail
Summary
  • Symbol
    Crybb3
  • Name
    crystallin, beta B3
  • Feature Type
    protein coding gene
  • IDs
    MGI:102717
    NCBI Gene: 12962
  • Gene Overview
    MyGene.info: CRYBB3
Location & Maps
more
  • Sequence Map
    Chr5:113075839-113081584 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5746 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 55.38 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    CRYBB3, crystallin beta B3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CRYBB3, crystallin beta B3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CATCN2, CRYB3, CTRCT22
  • Links
    NCBI Gene ID: 1417
    neXtProt AC: NX_P26998

  • Chr Location
    22q11.23; chr22:25198686-25207363 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human CRYBB3 associations

Human Disease Mouse Models
       Cataract 22, Multiple Types; CTRCT22   OMIM: 609741
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    5
  • Genomic Mutations
    2 involving Crybb3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026830 VEGA Gene Model | MGI Sequence Detail 5746 C57BL/6J ±  kb
transcript OTTMUST00000066357 VEGA | MGI Sequence Detail 816 Not Applicable  
polypeptide OTTMUSP00000033245 VEGA | MGI Sequence Detail 211 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    66 from dbSNP Build 142
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 3
    Primer pair 1
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-19621, MGI:2140996
References
more
  • Summaries
    All 31
    Developmental Gene Expression 6
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:23156 Hulsebos TJ, et al., The beta crystallin genes on human chromosome 22 define a new region of homology with mouse chromosome 5. Genomics. 1995 Jan 20;25(2):574-6
  • Latest
    J:178731 Xie Q, et al., The Orchestration of Mammalian Tissue Morphogenesis through a Series of Coherent Feed-forward Loops. J Biol Chem. 2011 Dec 16;286(50):43259-71

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory