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Crybb3 Gene Detail
Summary
  • Symbol
    Crybb3
  • Name
    crystallin, beta B3
  • Feature Type
    protein coding gene
  • IDs
    MGI:102717
    NCBI Gene: 12962
  • Gene Overview
    MyGene.info: CRYBB3
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:113075839-113081584 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 55.38 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    66 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102717
protein coding gene Chr5:113075839-113082233 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029913
protein coding gene Chr5:115706485-115712224 (-)
A/J MGP_AJ_G0029879
protein coding gene Chr5:111197965-111203694 (-)
AKR/J MGP_AKRJ_G0029817
protein coding gene Chr5:114725945-114731682 (-)
BALB/cJ MGP_BALBcJ_G0029890
protein coding gene Chr5:112559628-112565367 (-)
C3H/HeJ MGP_C3HHeJ_G0029610
protein coding gene Chr5:115159122-115164860 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030343
protein coding gene Chr5:120206531-120212276 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027572
protein coding gene Chr5:106013024-106018998 (-)
CAST/EiJ MGP_CASTEiJ_G0029018
protein coding gene Chr5:114084536-114090288 (-)
CBA/J MGP_CBAJ_G0029577
protein coding gene Chr5:124750791-124756529 (-)
DBA/2J MGP_DBA2J_G0029727
protein coding gene Chr5:111265667-111271404 (-)
FVB/NJ MGP_FVBNJ_G0029684
protein coding gene Chr5:110003990-110009729 (-)
LP/J MGP_LPJ_G0029815
protein coding gene Chr5:116271059-116276798 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029715
protein coding gene Chr5:129273137-129278874 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030384
protein coding gene Chr5:114160771-114166500 (-)
PWK/PhJ MGP_PWKPhJ_G0028732
protein coding gene Chr5:109880447-109886220 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028570
protein coding gene Chr5:111670254-111676025 (-)
WSB/EiJ MGP_WSBEiJ_G0029094
protein coding gene Chr5:114687030-114692768 (-)



Homology
more
  • Human Ortholog
    CRYBB3, crystallin beta B3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CRYBB3, crystallin beta B3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CATCN2, CRYB3, CTRCT22
  • Links
    NCBI Gene ID: 1417
    neXtProt AC: NX_P26998
    UniProt: P26998

  • Chr Location
    22q11.23; chr22:25199312-25207617 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human CRYBB3 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029352 Ensembl Gene Model | MGI Sequence Detail 5746 C57BL/6J ±  kb
transcript ENSMUST00000076069 Ensembl | MGI Sequence Detail 816 Not Applicable  
polypeptide ENSMUSP00000075440 Ensembl | MGI Sequence Detail 211 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 10
    Primer pair 1
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-19621, MGI:2140996
References
more
  • Summaries
    All 41
    Developmental Gene Expression 7
    Gene Ontology 2
    Phenotypes 12
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:246153 Logan CM, et al., N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis. Dev Biol. 2017 Aug 01;428(1):118-134

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory