About   Help   FAQ
Crybb3
Gene Detail
 Symbol
Name
ID
Crybb3
crystallin, beta B3
MGI:102717
Feature Type protein coding gene
Genetic Map
Chromosome 5
55.38 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr5:113075839-113081584 bp, - strand
From VEGA annotation of GRCm38

  5746 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3008  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: beta/gamma crystallins
Gene Tree: Crybb3

Human
homologs
Human Homolog CRYBB3, crystallin, beta B3
NCBI Gene ID 1417
neXtProt AC  NX_P26998
Human Synonyms  CATCN2, CRYB3, CTRCT22
Human Chr (Location)  22q11.23; chr22:25199850-25207359 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human CRYBB3
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Crybb3 interacts with 6 markers (Mir27a, Mir137, Mir325, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (1 annotations)
Function structural constituent of eye lens
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (18)    Tissues (2)    Images (2)
Theiler Stages: 19, 25
Assay TypeResults
RT-PCR 18
cDNA source data(3)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(5) cDNA(3) Primer pair(1) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000026830 (Evidence)
Ensembl Gene ModelENSMUSG00000029352 (Evidence)
Entrez Gene12962 (Evidence)
DFCITC1573737, TC1590478
DoTSDT.101390871, DT.102535255, DT.91415312, DT.99851511
NIA Mouse Gene IndexU026585
Consensus CDS ProjectCCDS19547.1
International Mouse Knockout Project StatusCrybb3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026830 VEGA Gene Model | MGI Sequence Detail 5746 C57BL/6J ±  kb
transcript OTTMUST00000066357 VEGA | MGI Sequence Detail 816 Not Applicable 
polypeptide OTTMUSP00000033245 VEGA | MGI Sequence Detail 211 Not Applicable 

For the selected sequences
All sequences(66) RefSeq(6) UniProt(5)
Polymorphisms RFLP(1) : SNPs within 2kb(66 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001064 Beta/gamma crystallin
InterPro IPR011024 Gamma-crystallin-related
Protein Ontology PR:000005913 beta-crystallin B3
References (Earliest) J:23156 Hulsebos TJ, et al., The beta crystallin genes on human chromosome 22 define a new region of homology with mouse chromosome 5. Genomics. 1995 Jan 20;25(2):574-6
(Latest) J:178731 Xie Q, et al., The Orchestration of Mammalian Tissue Morphogenesis through a Series of Coherent Feed-forward Loops. J Biol Chem. 2011 Dec 16;286(50):43259-71
All references(35)
Other
accession IDs
MGD-MRK-19621, MGI:2140996

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/19/2014
MGI 5.19
The Jackson Laboratory