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Cryba4 Gene Detail
Summary
  • Symbol
    Cryba4
  • Name
    crystallin, beta A4
  • Feature Type
    protein coding gene
  • IDs
    MGI:102716
    NCBI Gene: 12959
  • Gene Overview
    MyGene.info: CRYBA4
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:112246493-112252518 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 54.62 cM
  • Mapping Data
    7 experiments
Strain
Comparison
more
  • SNPs within 2kb
    34 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102716
protein coding gene Chr5:112246492-112263553 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029900
protein coding gene Chr5:114819490-114825489 (-)
A/J MGP_AJ_G0029866
protein coding gene Chr5:110348686-110354823 (-)
AKR/J MGP_AKRJ_G0029804
protein coding gene Chr5:113855756-113861767 (-)
BALB/cJ MGP_BALBcJ_G0029877
protein coding gene Chr5:111707805-111713850 (-)
C3H/HeJ MGP_C3HHeJ_G0029597
protein coding gene Chr5:114295403-114301403 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030330
protein coding gene Chr5:119304940-119310966 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027559
protein coding gene Chr5:105172278-105178463 (-)
CAST/EiJ MGP_CASTEiJ_G0029005
protein coding gene Chr5:113196410-113202431 (-)
CBA/J MGP_CBAJ_G0029564
protein coding gene Chr5:123781629-123787631 (-)
DBA/2J MGP_DBA2J_G0029714
protein coding gene Chr5:110414964-110420993 (-)
FVB/NJ MGP_FVBNJ_G0029671
protein coding gene Chr5:109137106-109143140 (-)
LP/J MGP_LPJ_G0029802
protein coding gene Chr5:115387217-115393587 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029702
protein coding gene Chr5:128361343-128367365 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030371
protein coding gene Chr5:113290092-113296112 (-)
PWK/PhJ MGP_PWKPhJ_G0028719
protein coding gene Chr5:109023344-109029359 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028557
protein coding gene Chr5:110773868-110779876 (-)
WSB/EiJ MGP_WSBEiJ_G0029081
protein coding gene Chr5:113802997-113809006 (-)



Homology
more
  • Human Ortholog
    CRYBA4, crystallin beta A4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CRYBA4, crystallin beta A4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CTRCT23, CYRBA4, MCOPCT4
  • Links
    NCBI Gene ID: 1413
    neXtProt AC: NX_P53673
    UniProt: P53673

  • Chr Location
    22q12.1; chr22:26607982-26630672 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human CRYBA4 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000066975 Ensembl Gene Model | MGI Sequence Detail 6026 C57BL/6J ±  kb
transcript ENSMUST00000112385 Ensembl | MGI Sequence Detail 808 Not Applicable  
polypeptide ENSMUSP00000108004 Ensembl | MGI Sequence Detail 196 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 88
    Genomic 1
    cDNA 85
    Primer pair 1
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-19620
References
more
  • Summaries
    All 41
    Developmental Gene Expression 5
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:178731 Xie Q, et al., The Orchestration of Mammalian Tissue Morphogenesis through a Series of Coherent Feed-forward Loops. J Biol Chem. 2011 Dec 16;286(50):43259-71

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory