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Gng2 Gene Detail
Summary
  • Symbol
    Gng2
  • Name
    guanine nucleotide binding protein (G protein), gamma 2
  • Synonyms
    1110003P13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:102705
    NCBI Gene: 14702
  • Gene Overview
    MyGene.info: GNG2
Location & Maps
more
  • Sequence Map
    Chr14:19872559-19977627 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      105069 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 11.17 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    GNG2, G protein subunit gamma 2
  • Vertebrate Orthologs
    11
  • Human Ortholog
    GNG2, G protein subunit gamma 2
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 54331
    neXtProt AC: NX_P59768

  • Chr Location
    14q21; chr14:51847131-51969800 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    70
  • Gene trapped
    68
  • Targeted
    2
  • Incidental Mutations
Mice homozygous for a knock-out allele exhibit reduced vomeronasal basal neurons, reduced posterior glomerular layer of the accessory olfactory bulb and decreased aggression towards male mice.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034627 VEGA Gene Model | MGI Sequence Detail 105069 C57BL/6J ±  kb
transcript OTTMUST00000087877 VEGA | MGI Sequence Detail 3826 Not Applicable  
polypeptide OTTMUSP00000047860 VEGA | MGI Sequence Detail 71 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    456 from dbSNP Build 142
  • RFLP
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000008107 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
  • InterPro Domains
    IPR015898 G-protein gamma-like domain
    IPR001770 G-protein, gamma subunit
Molecular
Reagents
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  • All nucleic 86
    Genomic 1
    cDNA 84
    Primer pair 1

    Microarray probesets 7
Other
Accession IDs
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MGD-MRK-19609, MGI:1923542
References
more
  • Summaries
    All 44
    Developmental Gene Expression 7
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:14624 Hurley JB, et al., Isolation and characterization of a cDNA clone for the gamma subunit of bovine retinal transducin. Proc Natl Acad Sci U S A. 1984 Nov;81(22):6948-52
  • Latest
    J:175792 Jelcick AS, et al., Genetic variations strongly influence phenotypic outcome in the mouse retina. PLoS One. 2011;6(7):e21858

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory