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Gng2 Gene Detail
Summary
  • Symbol
    Gng2
  • Name
    guanine nucleotide binding protein (G protein), gamma 2
  • Synonyms
    1110003P13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:102705
    NCBI Gene: 14702
  • Gene Overview
    MyGene.info: GNG2
  • Alliance
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:19872559-19977249 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 11.17 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    456 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102705
protein coding gene Chr14:19872559-19977627 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021026
protein coding gene Chr14:12590859-12711198 (-)
A/J MGP_AJ_G0020975
protein coding gene Chr14:12302266-12421700 (-)
AKR/J MGP_AKRJ_G0020952
protein coding gene Chr14:12812582-12930666 (-)
BALB/cJ MGP_BALBcJ_G0020978
protein coding gene Chr14:12433461-12541667 (-)
C3H/HeJ MGP_C3HHeJ_G0020762
protein coding gene Chr14:12743308-12867445 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021411
protein coding gene Chr14:13102521-13216555 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018979
protein coding gene Chr14:12643605-12748634 (-)
CAST/EiJ MGP_CASTEiJ_G0020286
protein coding gene Chr14:12501337-12615971 (-)
CBA/J MGP_CBAJ_G0020728
protein coding gene Chr14:13732815-13868354 (-)
DBA/2J MGP_DBA2J_G0020851
protein coding gene Chr14:12142223-12256516 (-)
FVB/NJ MGP_FVBNJ_G0020834
protein coding gene Chr14:12048065-12156718 (-)
LP/J MGP_LPJ_G0020927
protein coding gene Chr14:12810264-12927841 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020860
protein coding gene Chr14:13526741-13668170 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021444
protein coding gene Chr14:12620113-12727166 (-)
PWK/PhJ MGP_PWKPhJ_G0020035
protein coding gene Chr14:11668674-11794432 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019857
protein coding gene Chr14:12374773-12491725 (-)
WSB/EiJ MGP_WSBEiJ_G0020342
protein coding gene Chr14:12594830-12711486 (-)



Homology
more
  • Human Ortholog
    GNG2, G protein subunit gamma 2
  • Vertebrate Orthologs
    11
  • Human Ortholog
    GNG2, G protein subunit gamma 2
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 54331
    neXtProt AC: NX_P59768
    UniProt: P59768

  • Chr Location
    14q22.1; chr14:51847131-51969800 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Mice homozygous for a knock-out allele exhibit reduced vomeronasal basal neurons, reduced posterior glomerular layer of the accessory olfactory bulb and decreased aggression towards male mice.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 14702 NCBI Gene Model | MGI Sequence Detail 104691 C57BL/6J ±  kb
transcript NM_010315 RefSeq | MGI Sequence Detail 3826 C57BL/6  
polypeptide P63213 UniProt | EBI | MGI Sequence Detail 71 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR015898 G-protein gamma-like domain
    IPR036284 G-protein gamma-like domain superfamily
    IPR001770 G-protein, gamma subunit
Molecular
Reagents
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  • All nucleic 87
    Genomic 1
    cDNA 85
    Primer pair 1

    Microarray probesets 7
Other
Accession IDs
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MGD-MRK-19609, MGI:1923542
References
more
  • Summaries
    All 47
    Developmental Gene Expression 7
    Gene Ontology 7
    Phenotypes 6
  • Earliest
    J:14624 Hurley JB, et al., Isolation and characterization of a cDNA clone for the gamma subunit of bovine retinal transducin. Proc Natl Acad Sci U S A. 1984 Nov;81(22):6948-52
  • Latest
    J:212780 Montani G, et al., Aggressive behaviour and physiological responses to pheromones are strongly impaired in mice deficient for the olfactory G-protein -subunit G8. J Physiol. 2013 Aug 15;591(Pt 16):3949-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory