Gng2
Gene Detail

Symbol Name ID

Gng2 guanine nucleotide binding protein (G protein), gamma 2 MGI:102705

Synonyms

1110003P13Rik, 82

Feature Type

protein coding gene

Genetic Map

Chromosome 14

11.17 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr14:19872559-19977627 bp, - strand From VEGA annotation of GRCm38   105069 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:40715  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: GTP-binding regulatory protein gamma chain
Gene Tree: Gng2

Human homologs

Human Homolog		GNG2, guanine nucleotide binding protein (G protein), gamma 2
NCBI Gene ID		54331
neXtProt AC		NX_P59768
Human Chr (Location)		14q21; chr14:52327022-52436518 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(70) : Targeted(2) Gene trapped(68)

Gene Ontology (GO) classifications

All GO classifications: (11 annotations)

Process	cell proliferation, G-protein coupled receptor signaling pathway, ...
Component	heterotrimeric G-protein complex, membrane, ...
Function	GTPase activity, signal transducer activity

External Resources: FuncBase

Expression

Literature Summary: (7 records)
Data Summary: Results (127)    Tissues (55)    Images (34)
Theiler Stages: 1, 2, 3, 4, 17, 21, 23, 28

Assay Type	Results
RNA in situ	117
RT-PCR	10

cDNA source data(82)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(84) Genomic(1) cDNA(82) Primer pair(1)
Microarray probesets(7)

Other database links

VEGA Gene Model	OTTMUSG00000034627 (Evidence)
Ensembl Gene Model	ENSMUSG00000043004 (Evidence)
Entrez Gene	14702 (Evidence)
UniGene	41737
DFCI	TC1578816, TC1600613, TC1715923
DoTS	DT.94291796, DT.97373136
NIA Mouse Gene Index	U015357, U035268, U229673
Consensus CDS Project	CCDS26840.1
International Mouse Knockout Project Status	Gng2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000034627	VEGA Gene Model | MGI Sequence Detail	105069	C57BL/6J
transcript	OTTMUST00000087877	VEGA | MGI Sequence Detail	3826	Not Applicable
polypeptide	OTTMUSP00000047860	VEGA | MGI Sequence Detail	71	Not Applicable

All sequences(58) RefSeq(4) UniProt(1)

Polymorphisms

RFLP(1) : SNPs(434 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR015898	G-protein gamma-like domain
InterPro	IPR001770	G-protein, gamma subunit
Protein Ontology	PR:000008107	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

References

(Earliest) J:14624 Hurley JB, et al., Isolation and characterization of a cDNA clone for the gamma subunit of bovine retinal transducin. Proc Natl Acad Sci U S A. 1984 Nov;81(22):6948-52
(Latest) J:175792 Jelcick AS, et al., Genetic variations strongly influence phenotypic outcome in the mouse retina. PLoS One. 2011;6(7):e21858
All references(47)

Other accession IDs

MGD-MRK-19609, MGI:1923542