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Gng4 Gene Detail
Summary
  • Symbol
    Gng4
  • Name
    guanine nucleotide binding protein (G protein), gamma 4
  • Synonyms
    4
  • Feature Type
    protein coding gene
  • IDs
    MGI:102703
    NCBI Gene: 14706
  • Gene Overview
    MyGene.info: GNG4
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:13784059-13827895 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 5.29 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    362 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102703
protein coding gene Chr13:13784059-13827897 (.)
129S1/SvImJ MGP_129S1SvImJ_G0020237
protein coding gene Chr13:10733823-10781014 (+)
A/J MGP_AJ_G0020195
protein coding gene Chr13:10684347-10730112 (+)
AKR/J MGP_AKRJ_G0020169
protein coding gene Chr13:10791641-10838591 (+)
BALB/cJ MGP_BALBcJ_G0020181
protein coding gene Chr13:10669394-10713684 (+)
C3H/HeJ MGP_C3HHeJ_G0019985
protein coding gene Chr13:10958342-11003747 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020625
protein coding gene Chr13:11318919-11369055 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018231
protein coding gene Chr13:9445911-9489012 (+)
CAST/EiJ MGP_CASTEiJ_G0019519
protein coding gene Chr13:10596845-10643726 (+)
CBA/J MGP_CBAJ_G0019949
protein coding gene Chr13:11670455-11719202 (+)
DBA/2J MGP_DBA2J_G0020068
protein coding gene Chr13:10332692-10376968 (+)
FVB/NJ MGP_FVBNJ_G0020049
protein coding gene Chr13:10057899-10102060 (+)
LP/J MGP_LPJ_G0020138
protein coding gene Chr13:10935051-10979683 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020086
protein coding gene Chr13:11771701-11817412 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020652
protein coding gene Chr13:10595708-10645383 (+)
PWK/PhJ MGP_PWKPhJ_G0019282
protein coding gene Chr13:10425250-10471119 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019089
protein coding gene Chr13:9790252-9834331 (+)
WSB/EiJ MGP_WSBEiJ_G0019580
protein coding gene Chr13:10619223-10664305 (+)



Homology
more
  • Human Ortholog
    GNG4, G protein subunit gamma 4
  • Vertebrate Orthologs
    9
  • Human Ortholog
    GNG4, G protein subunit gamma 4
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 2786
    neXtProt AC: NX_P50150
    UniProt: P50150

  • Chr Location
    1q42.3; chr1:235547685-235650754 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 14706 NCBI Gene Model | MGI Sequence Detail 43837 C57BL/6J ±  kb
transcript NM_010317 RefSeq | MGI Sequence Detail 3200 C57BL/6  
polypeptide P50153 UniProt | EBI | MGI Sequence Detail 75 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    Genomic 3
    cDNA 21
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-19607
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:14657 Gautam N, et al., G protein diversity is increased by associations with a variety of gamma subunits. Proc Natl Acad Sci U S A. 1990 Oct;87(20):7973-7
  • Latest
    J:209428 Ragancokova D, et al., TSHZ1-dependent gene regulation is essential for olfactory bulb development and olfaction. J Clin Invest. 2014 Mar 3;124(3):1214-27

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory