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Mtcp1 Gene Detail
Summary
  • Symbol
    Mtcp1
  • Name
    mature T cell proliferation 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:102699
    NCBI Gene: 17763
  • Gene Overview
    MyGene.info: MTCP1
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:75410442-75416584 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 38.22 cM
Strain
Comparison
more
  • SNPs within 2kb
    64 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102699
protein coding gene ChrX:75410442-75416588 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035859
protein coding gene ChrX:71254550-71260704 (-)
A/J MGP_AJ_G0035846
protein coding gene ChrX:71475327-71481469 (-)
AKR/J MGP_AKRJ_G0035767
protein coding gene ChrX:73329537-73335659 (-)
BALB/cJ MGP_BALBcJ_G0035828
protein coding gene ChrX:70467597-70473721 (-)
C3H/HeJ MGP_C3HHeJ_G0035538
protein coding gene ChrX:71753880-71760022 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036358
protein coding gene ChrX:73533838-73539968 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033197
protein coding gene ChrX:70986175-70992224 (-)
CAST/EiJ MGP_CASTEiJ_G0034824
protein coding gene ChrX:57084494-57090642 (-)
CBA/J MGP_CBAJ_G0035511
protein coding gene ChrX:75498955-75505083 (-)
DBA/2J MGP_DBA2J_G0035669
protein coding gene ChrX:70928582-70934712 (-)
FVB/NJ MGP_FVBNJ_G0035610
protein coding gene ChrX:70254055-70260171 (-)
LP/J MGP_LPJ_G0035751
protein coding gene ChrX:72055222-72062358 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035644
protein coding gene ChrX:78113051-78119176 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036384
protein coding gene ChrX:71122553-71128685 (-)
PWK/PhJ MGP_PWKPhJ_G0034521
protein coding gene ChrX:55087978-55094101 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034357
protein coding gene ChrX:57884909-57891096 (-)
WSB/EiJ MGP_WSBEiJ_G0034963
protein coding gene ChrX:70327648-70333795 (-)



Homology
more
  • Human Ortholog
    CMC4, C-X9-C motif containing 4
  • Vertebrate Orthologs
    8
  • Human Ortholog
    CMC4, C-X9-C motif containing 4
    Orthology source: HomoloGene
  • Synonyms
    C6.1B, MTCP1, MTCP1B, MTCP1NB, p8, p8MTCP1
  • Links
    NCBI Gene ID: 100272147
    neXtProt AC: NX_P56277
    UniProt: P56277

  • Chr Location
    Xq28; chrX:155061622-155071272 (-)  GRCh38.p7

  • Human Ortholog
    MTCP1, mature T cell proliferation 1
    Orthology source: HGNC
  • Synonyms
    P13MTCP1, p8MTCP1
  • Links
    NCBI Gene ID: 4515
    neXtProt AC: NX_P56278
    UniProt: P56278

  • Chr Location
    Xq28; chrX:155064034-155071272 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 17763 NCBI Gene Model | MGI Sequence Detail 6143 C57BL/6J ±  kb
transcript NM_001039373 RefSeq | MGI Sequence Detail 1635 C57BL/6  
polypeptide Q60945 UniProt | EBI | MGI Sequence Detail 107 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 26
    cDNA 24
    Primer pair 2

    Microarray probesets 8
Other
Accession IDs
less
MGD-MRK-19603
References
more
  • Summaries
    All 24
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:21838 Soulier J, et al., The MTCP-1/c6.1B gene encodes for a cytoplasmic 8 kD protein overexpressed in T cell leukemia bearing a t(X;14) translocation. Oncogene. 1994 Dec;9(12):3565-70
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory