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Cdc27 Gene Detail
Summary
  • Symbol
    Cdc27
  • Name
    cell division cycle 27
  • Synonyms
    APC3
  • Feature Type
    protein coding gene
  • IDs
    MGI:102685
    NCBI Gene: 217232
  • Gene Overview
    MyGene.info: CDC27
Location & Maps
more
  • Sequence Map
    Chr11:104502745-104550620 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      47876 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 67.79 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    CDC27, cell division cycle 27
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CDC27, cell division cycle 27
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ANAPC3, APC3, CDC27Hs, D0S1430E, D17S978E, HNUC, H-NUC, NUC2
  • Links
    NCBI Gene ID: 996
    neXtProt AC: NX_P30260

  • Chr Location
    17q21.32; chr17:47117697-47189312 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 960
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: CDC27
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    22
  • Gene trapped
    20
  • Targeted
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003148 VEGA Gene Model | MGI Sequence Detail 47876 C57BL/6J ±  kb
transcript OTTMUST00000006502 VEGA | MGI Sequence Detail 3160 Not Applicable  
polypeptide OTTMUSP00000003074 VEGA | MGI Sequence Detail 831 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    209 from dbSNP Build 142
  • RFLP
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000005195 cell division cycle protein 27
  • InterPro Domains
    IPR011990 Tetratricopeptide-like helical domain
    IPR019734 Tetratricopeptide repeat
    IPR001440 Tetratricopeptide repeat 1
    IPR013026 Tetratricopeptide repeat-containing domain
Molecular
Reagents
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  • All nucleic 20
    cDNA 18
    Primer pair 1
    Other 1

    Microarray probesets 8
Other
Accession IDs
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MGD-MRK-19588, MGI:2144178, MGI:2384954
References
more
  • Summaries
    All 37
    Developmental Gene Expression 4
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:24091 Tugendreich S, et al., Linking yeast genetics to mammalian genomes: identification and mapping of the human homolog of CDC27 via the expressed sequence tag (EST) data base. Proc Natl Acad Sci U S A. 1993 Nov 1;90(21):10031-5
  • Latest
    J:187715 Xie L, et al., Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation. Dev Cell. 2012 Aug 14;23(2):280-91

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory