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Cdc27 Gene Detail
Summary
  • Symbol
    Cdc27
  • Name
    cell division cycle 27
  • Synonyms
    APC3
  • Feature Type
    protein coding gene
  • IDs
    MGI:102685
    NCBI Gene: 217232
  • Gene Overview
    MyGene.info: CDC27
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:104502745-104550620 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 67.79 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    209 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102685
protein coding gene Chr11:104502524-104550620 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019276
protein coding gene Chr11:107661649-107709603 (-)
A/J MGP_AJ_G0019244
protein coding gene Chr11:103082252-103130636 (-)
AKR/J MGP_AKRJ_G0019213
protein coding gene Chr11:106227602-106275463 (-)
BALB/cJ MGP_BALBcJ_G0019218
protein coding gene Chr11:103513858-103562243 (-)
C3H/HeJ MGP_C3HHeJ_G0019027
protein coding gene Chr11:106469822-106518612 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019668
protein coding gene Chr11:110982319-111042040 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017293
protein coding gene Chr11:100471643-100520068 (-)
CAST/EiJ MGP_CASTEiJ_G0018581
protein coding gene Chr11:107529585-107579324 (-)
CBA/J MGP_CBAJ_G0018996
protein coding gene Chr11:115592604-115643886 (-)
DBA/2J MGP_DBA2J_G0019108
protein coding gene Chr11:102567059-102616654 (-)
FVB/NJ MGP_FVBNJ_G0019099
protein coding gene Chr11:102105884-102154144 (-)
LP/J MGP_LPJ_G0019177
protein coding gene Chr11:108135730-108185957 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019129
protein coding gene Chr11:114911141-114962760 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019705
protein coding gene Chr11:106628015-106678762 (-)
PWK/PhJ MGP_PWKPhJ_G0018346
protein coding gene Chr11:103673161-103722241 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018136
protein coding gene Chr11:106399629-106450336 (-)
WSB/EiJ MGP_WSBEiJ_G0018630
protein coding gene Chr11:106641698-106690011 (-)



Homology
more
  • Human Ortholog
    CDC27, cell division cycle 27
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CDC27, cell division cycle 27
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ANAPC3, APC3, CDC27Hs, D0S1430E, D17S978E, HNUC, H-NUC, NUC2
  • Links
    NCBI Gene ID: 996
    neXtProt AC: NX_P30260
    UniProt: P30260

  • Chr Location
    17q21.32; chr17:47117697-47189332 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 960
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CDC27
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020687 Ensembl Gene Model | MGI Sequence Detail 47876 C57BL/6J ±  kb
transcript ENSMUST00000106962 Ensembl | MGI Sequence Detail 3160 Not Applicable  
polypeptide ENSMUSP00000102575 Ensembl | MGI Sequence Detail 831 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 19
    Primer pair 1

    Microarray probesets 8
Other
Accession IDs
less
MGD-MRK-19588, MGI:2144178, MGI:2384954
References
more
  • Summaries
    All 41
    Developmental Gene Expression 4
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:24091 Tugendreich S, et al., Linking yeast genetics to mammalian genomes: identification and mapping of the human homolog of CDC27 via the expressed sequence tag (EST) data base. Proc Natl Acad Sci U S A. 1993 Nov 1;90(21):10031-5
  • Latest
    J:221567 Huang J, et al., A Cdh1-APC/FMRP Ubiquitin Signaling Link Drives mGluR-Dependent Synaptic Plasticity in the Mammalian Brain. Neuron. 2015 May 6;86(3):726-39

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory