About   Help   FAQ
Cdc34
Gene Detail
 Symbol
Name
ID
Cdc34
cell division cycle 34
MGI:102657
Synonyms UBE2R1
Feature Type protein coding gene
Genetic Map
Chromosome 10
39.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr10:79682195-79688394 bp, + strand
From Ensembl annotation of GRCm38

  6200 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55815  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Protein SuperFamily: ubiquitin-conjugating enzyme E2
Gene Tree: Cdc34

Human
homologs
Human Homolog CDC34, cell division cycle 34
NCBI Gene ID 997
neXtProt AC  NX_P49427
Human Synonyms  E2-CDC34, UBC3, UBCH3, UBE2R1
Human Chr (Location)  19p13.3; chr19:531720-542092 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(26) : Gene trapped(23) Targeted(3)
Interactions
Cdc34 interacts with 46 markers (Mir28b, Mir28c, Mir93, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process cell cycle, negative regulation of cAMP-mediated signaling, ...
Component cytoplasm, nucleus
Function ATP binding, ligase activity, ...
External Resources: FuncBase
Expression
cDNA source data(127)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(127) cDNA(127)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000020307 (Evidence)
Entrez Gene216150 (Evidence)
UniGene21981
DFCITC1587256, TC1612857, TC1644028
DoTSDT.101125471, DT.110584809, DT.536661, DT.87033542
NIA Mouse Gene IndexU011717, U132557
EC6.3.2.19
Consensus CDS ProjectCCDS23983.1
International Mouse Knockout Project StatusCdc34
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020307 Ensembl Gene Model | MGI Sequence Detail 6200 C57BL/6J ±  kb
transcript ENSMUST00000020550 Ensembl | MGI Sequence Detail 1262 Not Applicable 
polypeptide ENSMUSP00000020550 Ensembl | MGI Sequence Detail 235 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(10) UniProt(1)
Polymorphisms SNPs within 2kb(40 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023313 Ubiquitin-conjugating enzyme, active site
InterPro IPR000608 Ubiquitin-conjugating enzyme, E2
InterPro IPR016135 Ubiquitin-conjugating enzyme/RWD-like
Protein Ontology PR:000005200 ubiquitin-conjugating enzyme E2 R1
References (Earliest) J:15595 Plon SE, et al., Cloning of the human homolog of the CDC34 cell cycle gene by complementation in yeast. Proc Natl Acad Sci U S A. 1993 Nov 15;90(22):10484-8
(Latest) J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
All references(37)
Other
accession IDs
MGD-MRK-19551, MGI:2143587

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/26/2014
MGI 5.19
The Jackson Laboratory