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Cdc34 Gene Detail
Summary
  • Symbol
    Cdc34
  • Name
    cell division cycle 34
  • Synonyms
    UBE2R1
  • Feature Type
    protein coding gene
  • IDs
    MGI:102657
    NCBI Gene: 216150
Location & Maps
more
  • Sequence Map
    Chr10:79682195-79688394 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      6200 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    CDC34, cell division cycle 34
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CDC34, cell division cycle 34
    Orthology source: HGNC, HomoloGene
  • Synonyms
    E2-CDC34, UBC3, UBCH3, UBE2R1
  • Links
    NCBI Gene ID: 997
    neXtProt AC: NX_P49427

  • Chr Location
    19p13.3; chr19:531719-542088 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    13 phenotype references
  • All Mutations and Alleles
    27
  • Chemically induced (other)
    1
  • Gene trapped
    23
  • Targeted
    3
  • Genomic Mutations
    1 involving Cdc34
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020307 Ensembl Gene Model | MGI Sequence Detail 6200 C57BL/6J ±  kb
transcript ENSMUST00000020550 Ensembl | MGI Sequence Detail 1262 Not Applicable  
polypeptide ENSMUSP00000020550 Ensembl | MGI Sequence Detail 235 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    40 from dbSNP Build 137
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 127
    cDNA 127

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-19551, MGI:2143587
References
more
  • Summaries
    All 34
    Gene Ontology 6
    Phenotypes 13
  • Earliest
    J:15595 Plon SE, et al., Cloning of the human homolog of the CDC34 cell cycle gene by complementation in yeast. Proc Natl Acad Sci U S A. 1993 Nov 15;90(22):10484-8
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory