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Crisp1
Gene Detail
Symbol

Name
ID
Crisp1
cysteine-rich secretory protein 1
MGI:102553
Synonyms
Aeg1, CRISP-1
Feature Type
protein coding gene
Genetic Map
Chromosome 17
19.47 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr17:40293758-40319207 bp, - strand
From VEGA annotation of GRCm38

  25450 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:135665  Vertebrate Homology Class
2 mouse; 1 rat; 1 cattle

Protein SuperFamily: cysteine-rich secretory protein 1
Gene Tree: Crisp1

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(1) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit reduced ability of sperm to fertilize eggs but no reduction in fertility.
 
Interactions
Crisp1 interacts with 103 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (2 annotations)
Component cytoplasmic vesicle, extracellular region
External Resources: FuncBase
Expression
cDNA source data(17)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(22) Genomic(4) cDNA(17) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000037980 (Evidence)
Ensembl Gene ModelENSMUSG00000025431 (Evidence)
Entrez Gene11571 (Evidence)
UniGene16781
DFCITC1578881
DoTSDT.50316723
NIA Mouse Gene IndexU037810
Consensus CDS ProjectCCDS28784.1
International Mouse Knockout Project StatusCrisp1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037980 VEGA Gene Model | MGI Sequence Detail 25450 C57BL/6J ±  kb
transcript OTTMUST00000097879 VEGA | MGI Sequence Detail 1416 Not Applicable 
polypeptide OTTMUSP00000054894 VEGA | MGI Sequence Detail 244 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(4) UniProt(5)
Polymorphisms
SNPs within 2kb(118 from dbSNP Build 137)    SNPs within 2kb including multiple locations(122)
Protein-related
information
ResourceIDDescription
InterPro IPR001283 Allergen V5/Tpx-1-related
InterPro IPR018244 Allergen V5/Tpx-1-related, conserved site
InterPro IPR014044 CAP domain
InterPro IPR013871 Cysteine-rich secretory protein
InterPro IPR003582 Metridin-like ShK toxin
Protein Ontology PR:000005878 cysteine-rich secretory protein 1
References
(Earliest) J:3169 Mizuki N, et al., Mouse submandibular glands express an androgen-regulated transcript encoding an acidic epididymal glycoprotein-like molecule. Mol Cell Endocrinol. 1992 Nov;89(1-2):25-32
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(39)
Other
accession IDs
MGD-MRK-19402, MGI:2147060

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory