mt-Co3
Gene Detail

Symbol Name ID

mt-Co3 mitochondrially encoded cytochrome c oxidase III MGI:102502

Synonyms

COIII, COX3

Feature Type

protein coding gene

Genetic Map

Chromosome MT
Syntenic

Sequence Map

ChrMT:8607-9390 bp, + strand From NCBI annotation of GRCm38   784 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:5014  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: mt-Co3

Human homologs

Human Homolog		COX3, cytochrome c oxidase III
NCBI Gene ID		4514
neXtProt AC		NX_P00414
Human Synonyms		COIII, MTCO3
Human Chr (Location)		MT
Disease Associations		(2) Diseases Associated with Human COX3

Gene Ontology (GO) classifications

All GO classifications: (5 annotations)

Process	oxidation-reduction process
Component	integral to membrane, membrane, ...
Function	oxidoreductase activity

External Resources: FuncBase

Expression

Literature Summary: (5 records)
Data Summary: Results (120)    Tissues (117)    Images (14)
Theiler Stages: 11, 20, 21, 22, 24, 26, 28

Assay Type	Results
RNA in situ	118
RT-PCR	2

cDNA source data(8)
External Resources: ArrayExpress

Molecular reagents

All nucleic(12) cDNA(10) Primer pair(1) Other(1)

Other database links

Ensembl Gene Model	ENSMUSG00000064358 (Evidence)
Entrez Gene	17710
DFCI	TC1727269
International Mouse Knockout Project Status	mt-Co3

Sequences

Length	Strain/Species
genomic	17710	NCBI Gene Model | MGI Sequence Detail	784	C57BL/6J
transcript	BC012020	GenBank | EMBL | DDBJ | MGI Sequence Detail	1616	C57BL/6
polypeptide	NP_904334	RefSeq | MGI Sequence Detail	261	C57BL/6J

All sequences(59) RefSeq(1) UniProt(1)

Protein-related information

Resource	ID	Description
InterPro	IPR000298	Cytochrome c oxidase, subunit III
InterPro	IPR013833	Cytochrome c oxidase, subunit III, 4-helical bundle
InterPro	IPR024791	Cytochrome c/ubiquinol oxidase subunit III
Protein Ontology	PR:000010689	cytochrome c oxidase subunit 3
Protein Ontology	PR:000025367	cytochrome c oxidase subunit 3 (mouse)

References

(Earliest) J:22484 Bibb MJ, et al., Sequence and gene organization of mouse mitochondrial DNA. Cell. 1981 Oct;26(2 Pt 2):167-80
(Latest) J:143901 Yu X, et al., Dissecting the effects of mtDNA variations on complex traits using mouse conplastic strains. Genome Res. 2009 Jan;19(1):159-65
All references(32)

Other accession IDs

MGD-MRK-19339, MGI:2138394, MGI:2138420, MGI:2138462, MGI:2138508