About   Help   FAQ
mt-Co3
Gene Detail
 Symbol
Name
ID
mt-Co3
mitochondrially encoded cytochrome c oxidase III
MGI:102502
Synonyms COIII, COX3
Feature Type protein coding gene
Genetic Map
Chromosome MT
Syntenic
Sequence Map
ChrMT:8607-9390 bp, + strand
From NCBI annotation of GRCm38

  784 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5014  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: mt-Co3

Human
homologs
Human Homolog COX3, cytochrome c oxidase III
NCBI Gene ID 4514
neXtProt AC  NX_P00414
Human Synonyms  COIII, MTCO3
Human Chr (Location)  MT
Disease Associations  (2) Diseases Associated with Human COX3
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process aerobic electron transport chain, oxidation-reduction process, ...
Component integral component of membrane, membrane, ...
Function cytochrome-c oxidase activity, heme-copper terminal oxidase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (120)    Tissues (117)    Images (14)
Theiler Stages: 11, 20, 21, 22, 24, 26, 28
Assay TypeResults
RNA in situ 118
RT-PCR 2
cDNA source data(8)
External Resources: ArrayExpress
Molecular
reagents
All nucleic(12) cDNA(10) Primer pair(1) Other(1)
Other database
links
Ensembl Gene ModelENSMUSG00000064358 (Evidence)
Entrez Gene17710
DFCITC1727269
International Mouse Knockout Project Statusmt-Co3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 17710 NCBI Gene Model | MGI Sequence Detail 784 C57BL/6J ±  kb
transcript BC012020 GenBank | EMBL | DDBJ | MGI Sequence Detail 1616 C57BL/6 
polypeptide P00416 UniProt | EBI | MGI Sequence Detail 261 Not Applicable 

For the selected sequences
All sequences(60) RefSeq(1) UniProt(2)
Polymorphisms SNPs within 2kb(12 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000298 Cytochrome c oxidase, subunit III
InterPro IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle
InterPro IPR024791 Cytochrome c/ubiquinol oxidase subunit III
Protein Ontology PR:000010689 cytochrome c oxidase subunit 3
Graphical View of Protein Domain Structure
References (Earliest) J:22484 Bibb MJ, et al., Sequence and gene organization of mouse mitochondrial DNA. Cell. 1981 Oct;26(2 Pt 2):167-80
(Latest) J:143901 Yu X, et al., Dissecting the effects of mtDNA variations on complex traits using mouse conplastic strains. Genome Res. 2009 Jan;19(1):159-65
All references(33)
Other
accession IDs
MGD-MRK-19339, MGI:2138394, MGI:2138420, MGI:2138462, MGI:2138508

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/15/2014
MGI 5.17
The Jackson Laboratory