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mt-Cytb Gene Detail
Summary
  • Symbol
    mt-Cytb
  • Name
    mitochondrially encoded cytochrome b
  • Synonyms
    Cytb
  • Feature Type
    protein coding gene
  • IDs
    MGI:102501
    NCBI Gene: 17711
  • Gene Overview
    MyGene.info: CYTB
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrMT:14145-15288 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome MT, Syntenic
Strain
Comparison
more
  • SNPs within 2kb
    8 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102501
protein coding gene ChrMT:14145-15288 (.)
129S1/SvImJ MGP_129S1SvImJ_G0028394
protein coding gene Chr4:79519709-79520852 (+)
A/J MGP_AJ_G0028355
protein coding gene Chr4:76773700-76775569 (+)
AKR/J MGP_AKRJ_G0028303
protein coding gene Chr4:78705573-78709625 (+)
BALB/cJ MGP_BALBcJ_G0028375
protein coding gene Chr4:76987274-76988417 (+)
C3H/HeJ MGP_C3HHeJ_G0028090
protein coding gene Chr4:79331140-79333838 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028814
protein coding gene Chr4:82626600-82627743 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0027531
protein coding gene Chr4:77313801-77314944 (+)
CBA/J MGP_CBAJ_G0028059
protein coding gene Chr4:85222783-85223926 (+)
DBA/2J MGP_DBA2J_G0028208
protein coding gene Chr4:76520040-76521183 (+)
FVB/NJ MGP_FVBNJ_G0028174
protein coding gene Chr4:75547748-75548891 (+)
LP/J MGP_LPJ_G0028308
protein coding gene Chr4:79863417-79864560 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028203
protein coding gene Chr4:90147201-90148344 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028851
protein coding gene Chr4:78836313-78837456 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0027607
protein coding gene Chr4:78951974-78953117 (+)



Homology
more
  • Human Ortholog
    CYTB, cytochrome b
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CYTB, cytochrome b
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MTCYB
  • Links
    NCBI Gene ID: 4519
    neXtProt AC: NX_P00156
    UniProt: P00156

  • Chr Location
    MT

Human Diseases
more
  • Diseases
    2 with human CYTB associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic 17711 NCBI Gene Model | MGI Sequence Detail 1144 C57BL/6J ±  kb
transcript BC004586 GenBank | EMBL | DDBJ | MGI Sequence Detail 1152 CZECHII  
polypeptide P00158 UniProt | EBI | MGI Sequence Detail 381 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 69
    cDNA 17
    Other 52

    Microarray probesets 1
Other
Accession IDs
less
MGD-MRK-19338, MGI:2140441, MGI:2140442, MGI:2140448, MGI:2141054
References
more
  • Summaries
    All 42
    Developmental Gene Expression 8
    Gene Ontology 7
    Phenotypes 3
  • Earliest
    J:22484 Bibb MJ, et al., Sequence and gene organization of mouse mitochondrial DNA. Cell. 1981 Oct;26(2 Pt 2):167-80
  • Latest
    J:263836 Srivillibhuthur M, et al., TFAM is required for maturation of the fetal and adult intestinal epithelium. Dev Biol. 2018 Jul 15;439(2):92-101

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory