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mt-Cytb Gene Detail
Summary
  • Symbol
    mt-Cytb
  • Name
    mitochondrially encoded cytochrome b
  • Synonyms
    Cytb
  • Feature Type
    protein coding gene
  • IDs
    MGI:102501
    NCBI Gene: 17711
  • Gene Overview
    MyGene.info: CYTB
Location & Maps
more
  • Genetic Map
    Chromosome MT, Syntenic
Homology
more
  • Human Ortholog
    CYTB, cytochrome b
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CYTB, cytochrome b
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MTCYB
  • Links
    NCBI Gene ID: 4519
    neXtProt AC: NX_P00156

  • Chr Location
    MT

Human Diseases
more
  • Diseases
    2 with human CYTB associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic 17711 NCBI Gene Model | MGI Sequence Detail 1144 C57BL/6J ±  kb
transcript BC004586 GenBank | EMBL | DDBJ | MGI Sequence Detail 1152 CZECHII  
polypeptide P00158 UniProt | EBI | MGI Sequence Detail 381 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    8 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 67
    cDNA 15
    Other 52

    Microarray probesets 1
Other
Accession IDs
less
MGD-MRK-19338, MGI:2140441, MGI:2140442, MGI:2140448, MGI:2141054
References
more
  • Summaries
    All 38
    Developmental Gene Expression 6
    Gene Ontology 7
    Phenotypes 3
  • Earliest
    J:22484 Bibb MJ, et al., Sequence and gene organization of mouse mitochondrial DNA. Cell. 1981 Oct;26(2 Pt 2):167-80
  • Latest
    J:235644 Wu Y, et al., Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury. PLoS Genet. 2016 Sep;12(9):e1006355

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/20/2017
MGI 6.10
The Jackson Laboratory