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mt-Nd4l Gene Detail
Summary
  • Symbol
    mt-Nd4l
  • Name
    mitochondrially encoded NADH dehydrogenase 4L
  • Synonyms
    ENSMUSG00000065947, URF4L
  • Feature Type
    protein coding gene
  • IDs
    MGI:102497
    NCBI Gene: 17720
  • Gene Overview
    MyGene.info: ND4L
Location & Maps
more
  • Genetic Map
    Chromosome MT, Syntenic
  • Mapping Data
    1 experiment
Homology
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  • Human Ortholog
    ND4L, NADH dehydrogenase, subunit 4L (complex I)
  • Vertebrate Orthologs
    6
  • Human Ortholog
    ND4L, NADH dehydrogenase, subunit 4L (complex I)
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MTND4L
  • Links
    NCBI Gene ID: 4539
    neXtProt AC: NX_P03901

  • Chr Location
    MT

Human Diseases
more
  • Diseases
    1 with human ND4L associations

Human Disease Mouse Models
       Leber Optic Atrophy   OMIM: 535000
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    1
  • Spontaneous
    1
  • Genomic Mutations
    1 involving mt-Nd4l
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000065947 Ensembl Gene Model | MGI Sequence Detail 297 C57BL/6J ±  kb
transcript ENSMUST00000084013 Ensembl | MGI Sequence Detail 297 Not Applicable  
polypeptide ENSMUSP00000081021 Ensembl | MGI Sequence Detail 98 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    29 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 59
    cDNA 6
    Primer pair 1
    Other 52

    Microarray probesets 2
Other
Accession IDs
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MGD-MRK-19334, MGI:3710614
References
more
  • Summaries
    All 19
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 12
  • Earliest
    J:22484 Bibb MJ, et al., Sequence and gene organization of mouse mitochondrial DNA. Cell. 1981 Oct;26(2 Pt 2):167-80
  • Latest
    J:143901 Yu X, et al., Dissecting the effects of mtDNA variations on complex traits using mouse conplastic strains. Genome Res. 2009 Jan;19(1):159-65

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory