mt-Nd5
Gene Detail

Symbol Name ID

mt-Nd5 mitochondrially encoded NADH dehydrogenase 5 MGI:102496

Synonyms

0610010I05Rik, URF5

Feature Type

protein coding gene

Genetic Map

Chromosome MT
Syntenic

Sequence Map

ChrMT:11742-13565 bp, + strand From NCBI annotation of GRCm38   1824 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:36212  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: NADH dehydrogenase (ubiquinone) chain 5
Gene Tree: mt-Nd5

Human homologs

Human Homolog		ND5, NADH dehydrogenase, subunit 5 (complex I)
NCBI Gene ID		4540
neXtProt AC		NX_P03915
Human Synonyms		MTND5
Human Chr (Location)		MT
Disease Associations		(2) Diseases Associated with Human ND5

Alleles and phenotypes

All alleles(1) : Gene trapped(1)

Gene Ontology (GO) classifications

All GO classifications: (12 annotations)

Process	electron transport chain, oxidation-reduction process, ...
Component	integral to membrane, membrane, ...
Function	NADH dehydrogenase activity, NADH dehydrogenase (ubiquinone) activity, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (43)    Tissues (29)    Images (13)
Theiler Stages: 19, 23, 28

Assay Type	Results
RNA in situ	43

cDNA source data(5)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(57) cDNA(5) Other(52)
Microarray probesets(1)

Other database links

Ensembl Gene Model	ENSMUSG00000064367 (Evidence)
Entrez Gene	17721
EC	1.6.5.3
International Mouse Knockout Project Status	mt-Nd5

Sequences

Length	Strain/Species
genomic	17721	NCBI Gene Model | MGI Sequence Detail	1824	C57BL/6J
transcript	BC055066	GenBank | EMBL | DDBJ | MGI Sequence Detail	5623	C57BL/6J
polypeptide	NP_904338	RefSeq | MGI Sequence Detail	607	C57BL/6J

All sequences(49) RefSeq(1) UniProt(2)

Protein-related information

Resource	ID	Description
InterPro	IPR010934	NADH dehydrogenase subunit 5, C-terminal
InterPro	IPR003945	NADH-plastoquinone oxidoreductase, chain 5
InterPro	IPR001516	NADH:ubiquinone oxidoreductase, chain 5/L, N-terminal
InterPro	IPR001750	NADH:ubiquinone/plastoquinone oxidoreductase

References

(Earliest) J:22484 Bibb MJ, et al., Sequence and gene organization of mouse mitochondrial DNA. Cell. 1981 Oct;26(2 Pt 2):167-80
(Latest) J:162575 Perales-Clemente E, et al., Five entry points of the mitochondrially encoded subunits in mammalian complex I assembly. Mol Cell Biol. 2010 Jun;30(12):3038-47
All references(30)

Other accession IDs

MGD-MRK-19333, MGI:1925612, MGI:2145345, MGI:2145346