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mt-Nd5
Gene Detail
Symbol

Name
ID
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
MGI:102496
Synonyms
0610010I05Rik, URF5
Feature Type
protein coding gene
Genetic Map
Chromosome MT
Syntenic
Sequence Map
ChrMT:11742-13565 bp, + strand
From Ensembl annotation of GRCm38

  1824 bp   ±  kb flank

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Mouse Genome Browser
Vertebrate
homology
HomoloGene:36212  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: NADH dehydrogenase (ubiquinone) chain 5
Gene Tree: mt-Nd5

Human
homologs
Human Homolog ND5, NADH dehydrogenase, subunit 5 (complex I)
NCBI Gene ID 4540
neXtProt AC  NX_P03915
Human Synonyms  MTND5
Human Chr (Location)  MT
Disease Associations  (2) Diseases Associated with Human ND5
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Gene trapped(1)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process oxidation-reduction process
Component mitochondrion, neuron projection
Function NADH dehydrogenase activity, NADH dehydrogenase (ubiquinone) activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (43)    Tissues (29)    Images (13)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 43
cDNA source data(5)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(57) cDNA(5) Other(52)
Microarray probesets(1)
Other database
links
Ensembl Gene ModelENSMUSG00000064367 (Evidence)
Entrez Gene17721
EC1.6.5.3
International Mouse Knockout Project Statusmt-Nd5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000064367 Ensembl Gene Model | MGI Sequence Detail 1824 C57BL/6J ±  kb
transcript ENSMUST00000082418 Ensembl | MGI Sequence Detail 1824 Not Applicable 
polypeptide ENSMUSP00000081001 Ensembl | MGI Sequence Detail 607 Not Applicable 

For the selected sequences
All sequences(50) RefSeq(1) UniProt(4)
Polymorphisms
SNPs within 2kb(103 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR010934 NADH dehydrogenase subunit 5, C-terminal
InterPro IPR003945 NADH-plastoquinone oxidoreductase, chain 5
InterPro IPR001516 NADH:ubiquinone oxidoreductase, chain 5/L, N-terminal
InterPro IPR001750 NADH:ubiquinone/plastoquinone oxidoreductase
References
(Earliest) J:22484 Bibb MJ, et al., Sequence and gene organization of mouse mitochondrial DNA. Cell. 1981 Oct;26(2 Pt 2):167-80
(Latest) J:162575 Perales-Clemente E, et al., Five entry points of the mitochondrially encoded subunits in mammalian complex I assembly. Mol Cell Biol. 2010 Jun;30(12):3038-47
All references(28)
Other
accession IDs
MGD-MRK-19333, MGI:1925612, MGI:2145345, MGI:2145346

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory