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mt-Tl2 Gene Detail
Summary
  • Symbol
    mt-Tl2
  • Name
    mitochondrially encoded tRNA leucine 2
  • Synonyms
    tRNA, tRNA-Leu, tRNA_Leu_2, TrnL2 tRNA
  • Feature Type
    tRNA gene
  • IDs
    MGI:102481
    NCBI Gene: 17736
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrMT:11671-11741 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome MT, Syntenic
Strain
Comparison
more
  • Strain Annotations
    2
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102481
tRNA gene ChrMT:11671-11741 (+)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0000392
tRNA gene Chr18:67756827-67756890 (+)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    TRNL2, tRNA
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRNL2, tRNA
  • Synonyms
    MTTL2
  • Links
    NCBI Gene ID: 4568

  • Chr Location
    MT

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
Sequences &
Gene Models
less
  • All Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 17736 NCBI Gene Model | MGI Sequence Detail 71 C57BL/6J ±  kb
For the selected sequence
Molecular
Reagents
less
  • All nucleic 52
    Other 52
Other
Accession IDs
less
MGD-MRK-19318
References
more
  • Summaries
    All 26
    Diseases 1
    Gene Ontology 1
    Phenotypes 14
  • Earliest
    J:22484 Bibb MJ, et al., Sequence and gene organization of mouse mitochondrial DNA. Cell. 1981 Oct;26(2 Pt 2):167-80
  • Latest
    J:303932 Ishikawa K, et al., Attempts to understand the mechanisms of mitochondrial diseases: The reverse genetics of mouse models for mitochondrial disease. Biochim Biophys Acta Gen Subj. 2021 Mar;1865(3):129835

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/12/2021
MGI 6.17
The Jackson Laboratory