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Fabp7
Gene Detail
Symbol

Name
ID
Fabp7
fatty acid binding protein 7, brain
MGI:101916
Synonyms
BFABP, B-FABP, Blbp
Feature Type
protein coding gene
Genetic Map
Chromosome 10
29.25 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr10:57784881-57788450 bp, + strand
From VEGA annotation of GRCm38

  3570 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37880  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: FABP7
Protein SuperFamily: lipid binding protein, FABP type
Gene Tree: Fabp7

Human
homologs
FABP7, fatty acid binding protein 7, brain
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 2173
neXtProt AC: NX_O15540

Human Synonyms: B-FABP, BLBP, FABPB, LTR2-FABP7, MRG

Human Chr (Location): 6q22-q23; chr6:122779501-122784074 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit increased fear memory, increased anxiety, and decreased sensitivity to DHA-induced NMDA currents.
 
Interactions
Fabp7 interacts with 37 markers (Mir29b-1, Mir29b-2, Mir33, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process cell proliferation in forebrain, epithelial cell proliferation, ...
Component cell body, cell-cell junction, ...
Function fatty acid binding, lipid binding, ...
External Resources: FuncBase
Expression
Literature Summary: (185 records)
Data Summary: Results (352)    Tissues (131)    Images (102)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 91
RNA in situ 245
Northern blot 8
Western blot 8
cDNA source data(39)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: GEISHA FABP7 ; Xenbase fabp7 ; ZFIN fabp7a, fabp7b    NEW 
Molecular
reagents
All nucleic(42) Genomic(1) cDNA(40) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000035387 (Evidence)
Ensembl Gene Model ENSMUSG00000019874 (Evidence)
Entrez Gene 12140 (Evidence)
UniGene 3644
DFCI TC1579089
DoTS DT.486583
NIA Mouse Gene Index U011535
Consensus CDS Project CCDS23856.1
International Mouse Phenotyping Consortium Status Fabp7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035387 VEGA Gene Model | MGI Sequence Detail 3570 C57BL/6J ±  kb
transcript OTTMUST00000090489 VEGA | MGI Sequence Detail 880 Not Applicable 
polypeptide OTTMUSP00000049663 VEGA | MGI Sequence Detail 188 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(44 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012674 Calycin
InterPro IPR011038 Calycin-like
InterPro IPR000463 Cytosolic fatty-acid binding
InterPro IPR000566 Lipocalin/cytosolic fatty-acid binding protein domain
Protein Ontology PR:000007315 fatty acid-binding protein, brain
References
(Earliest) J:25194 Hayes C, et al., Expression of the neu oncogene under the transcriptional control of the myelin basic protein gene in transgenic mice: generation of transformed glial cells. J Neurosci Res. 1992 Jan;31(1):175-87
(Latest) J:220872 Kagawa Y, et al., Fatty acid-binding protein 7 regulates function of caveolae in astrocytes through expression of caveolin-1. Glia. 2015 May;63(5):780-94
All references(226)
Other
accession IDs
MGD-MRK-18745

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory