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Gpr3
Gene Detail
 Symbol
Name
ID
Gpr3
G-protein coupled receptor 3
MGI:101908
Synonyms Gpcr21, Gpcr3
Feature Type protein coding gene
Genetic Map
Chromosome 4
66.24 cM, cytoband D3
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr4:133209340-133212536 bp, - strand
From VEGA annotation of GRCm38

  3197 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:31303  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: GPR6-like G protein-coupled receptor
Gene Tree: Gpr3

Human
homologs
Human Homolog GPR3, G protein-coupled receptor 3
NCBI Gene ID 2827
neXtProt AC  NX_P46089
Human Synonyms  ACCA
Human Chr (Location)  1p36.1-p35; chr1:27392644-27395814 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for one allele display an increased thermal nociceptive threshold while females homozygous for another allele display age-related reproductive failure due to ovulation of a progressively increasing proportion of developmentally incompetent oocytes.
 
Phenotype Images(1)
Interactions
Gpr3 interacts with 173 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process G-protein coupled receptor signaling pathway, positive regulation of cAMP metabolic process, ...
Component cell, cytosol, ...
Function G-protein coupled receptor activity, signal transducer activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (130)    Tissues (70)    Images (36)
Theiler Stages: 28
Assay TypeResults
In situ reporter (knock in) 92
RT-PCR 38
cDNA source data(9)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(10) cDNA(9) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000010474 (Evidence)
Ensembl Gene ModelENSMUSG00000049649 (Evidence)
Entrez Gene14748 (Evidence)
UniGene4721
DFCITC1587207, TC1622156
DoTSDT.110843563, DT.40139881
NIA Mouse Gene IndexU127424
Consensus CDS ProjectCCDS18743.1
International Mouse Knockout Project StatusGpr3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000010474 VEGA Gene Model | MGI Sequence Detail 3197 C57BL/6J ±  kb
transcript OTTMUST00000024395 VEGA | MGI Sequence Detail 2518 Not Applicable 
polypeptide OTTMUSP00000011224 VEGA | MGI Sequence Detail 330 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(77 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000984 G protein-coupled receptor 3
InterPro IPR000723 G protein-coupled receptor 3/6/12 orphan
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
Protein Ontology PR:000001643 G-protein coupled receptor 3
References (Earliest) J:16169 Saeki Y, et al., Molecular cloning of a novel putative G protein-coupled receptor (GPCR21) which is expressed predominantly in mouse central nervous system. FEBS Lett. 1993 Dec 27;336(2):317-22
(Latest) J:181834 Su YQ, et al., MARF1 regulates essential oogenic processes in mice. Science. 2012 Mar 23;335(6075):1496-9
All references(37)
Other
accession IDs
MGD-MRK-16342, MGD-MRK-18737

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory