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Klra2 Gene Detail
Summary
  • Symbol
    Klra2
  • Name
    killer cell lectin-like receptor, subfamily A, member 2
  • Synonyms
    Ly49b
  • Feature Type
    protein coding gene
  • IDs
    MGI:101906
    NCBI Gene: 16633
  • Member of
    Klra cluster
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:131219223-131247362 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 63.44 cM
  • Mapping Data
    7 experiments
Strain
Comparison
more
  • SNPs within 2kb
    399 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_101906
protein coding gene Chr6:131198970-131247716 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031365
protein coding gene Chr6:135147743-135175478 (-)
A/J MGP_AJ_G0031342
protein coding gene Chr6:129898067-129923412 (-)
AKR/J MGP_AKRJ_G0031270
protein coding gene Chr6:133662745-133691768 (-)
BALB/cJ MGP_BALBcJ_G0031349
protein coding gene Chr6:129572903-129597065 (-)
C3H/HeJ MGP_C3HHeJ_G0031072
protein coding gene Chr6:133772396-133795190 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031807
protein coding gene Chr6:138765492-138790203 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028944
protein coding gene Chr6:128183223-128213099 (-)
CAST/EiJ MGP_CASTEiJ_G0030443
protein coding gene Chr6:133678126-133714114 (-)
CBA/J MGP_CBAJ_G0031030
protein coding gene Chr6:144086725-144114642 (-)
DBA/2J MGP_DBA2J_G0031190
protein coding gene Chr6:128805022-128831863 (-)
FVB/NJ MGP_FVBNJ_G0031139
protein coding gene Chr6:127707167-127731145 (-)
LP/J MGP_LPJ_G0031270
protein coding gene Chr6:135454536-135482116 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031178
protein coding gene Chr6:148008877-148045730 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031840
protein coding gene Chr6:133550955-133576752 (-)
PWK/PhJ MGP_PWKPhJ_G0030163
protein coding gene Chr6:127199894-127226914 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029991
protein coding gene Chr6:131803208-131833365 (-)
WSB/EiJ MGP_WSBEiJ_G0030530
protein coding gene Chr6:134125542-134153818 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030187 Ensembl Gene Model | MGI Sequence Detail 28140 C57BL/6J ±  kb
transcript ENSMUST00000088867 Ensembl | MGI Sequence Detail 1132 Not Applicable  
polypeptide ENSMUSP00000086252 Ensembl | MGI Sequence Detail 321 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    Genomic 12
    cDNA 7
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-18733
References
more
  • Summaries
    All 32
    Gene Ontology 2
  • Earliest
    J:10723 Yokoyama WM, et al., Chromosomal location of the Ly-49 (A1, YE1/48) multigene family. Genetic association with the NK 1.1 antigen. J Immunol. 1990 Oct 1;145(7):2353-8
  • Latest
    J:209402 Mickiewicz KM, et al., Mutagenesis of Ly49B reveals key structural elements required for promiscuous binding to MHC class I molecules and new insights into the molecular evolution of Ly49s. J Immunol. 2014 Feb 15;192(4):1558-69

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory