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Klra3 Gene Detail
Summary
  • Symbol
    Klra3
  • Name
    killer cell lectin-like receptor, subfamily A, member 3
  • Synonyms
    5E6, Ly49c, Ly49C, Nk2, Nk-2, Nk2.1, NK-2.1
  • Feature Type
    protein coding gene
  • IDs
    MGI:101905
    NCBI Gene: 16634
  • Member of
    Klra cluster
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:130323289-130337574 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 63.44 cM
  • Mapping Data
    12 experiments
Strain
Comparison
more
  • SNPs within 2kb
    168 from dbSNP Build 142
  • Strain Annotations
    11
  • PCR
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_101905
protein coding gene Chr6:130323289-130337626 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0031339
protein coding gene Chr6:128849720-128864442 (-)
AKR/J MGP_AKRJ_G0031266
protein coding gene Chr6:132347550-132363289 (-)
BALB/cJ MGP_BALBcJ_G0031346
protein coding gene Chr6:128604226-128618432 (-)
C3H/HeJ MGP_C3HHeJ_G0031069
protein coding gene Chr6:132571190-132586646 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031804
protein coding gene Chr6:137465162-137695504 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0031026
protein coding gene Chr6:142992171-143008844 (-)
DBA/2J MGP_DBA2J_G0031187
protein coding gene Chr6:127816674-127830814 (-)
FVB/NJ MGP_FVBNJ_G0031135
protein coding gene Chr6:126468543-126482467 (-)
LP/J MGP_LPJ_G0031264
protein coding gene Chr6:133877399-133894714 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031169
protein coding gene Chr6:146378233-146554743 (-)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000067591 Ensembl Gene Model | MGI Sequence Detail 14286 C57BL/6J ±  kb
transcript ENSMUST00000088017 Ensembl | MGI Sequence Detail 984 Not Applicable  
polypeptide ENSMUSP00000085333 Ensembl | MGI Sequence Detail 266 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 40
    Genomic 19
    cDNA 18
    Primer pair 3

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-12882, MGD-MRK-12884, MGD-MRK-18732, MGI:97345
References
more
  • Summaries
    All 44
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:6490 Burton RC, et al., Studies on natural killer (NK) cells. I. NK cell specific antibodies in CE anti-CBA serum. J Immunol. 1981 May;126(5):1985-9
  • Latest
    J:267264 Shi L, et al., Modulation of NKG2D, NKp46, and Ly49C/I facilitates natural killer cell-mediated control of lung cancer. Proc Natl Acad Sci U S A. 2018 Nov 13;115(46):11808-11813

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/18/2019
MGI 6.14
The Jackson Laboratory