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Klra5 Gene Detail
Summary
  • Symbol
    Klra5
  • Name
    killer cell lectin-like receptor, subfamily A, member 5
  • Synonyms
    Ly49e
  • Feature Type
    protein coding gene
  • IDs
    MGI:101903
    NCBI Gene: 16636
  • Member of
    Klra cluster
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr6:129898988-129913224 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 63.44 cM
  • Mapping Data
    9 experiments
Strain
Comparison
more
  • SNPs within 2kb
    263 from dbSNP Build 142
  • Strain Annotations
    15
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_101903
protein coding gene Chr6:129898988-129917650 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031362
protein coding gene Chr6:133600074-133604227 (-)
A/J MGP_AJ_G0031333
protein coding gene Chr6:128464604-128484698 (-)
AKR/J MGP_AKRJ_G0031261
protein coding gene Chr6:131949640-131970600 (-)
BALB/cJ MGP_BALBcJ_G0031340
protein coding gene Chr6:128100848-128123045 (-)
C3H/HeJ MGP_C3HHeJ_G0031063
protein coding gene Chr6:132180569-132198695 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031799
protein coding gene Chr6:137213070-137372875 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0031024
protein coding gene Chr6:142460285-142482434 (-)
DBA/2J MGP_DBA2J_G0031182
protein coding gene Chr6:127404136-127421978 (-)
FVB/NJ MGP_FVBNJ_G0031131
protein coding gene Chr6:126312051-126330872 (-)
LP/J MGP_LPJ_G0031262
protein coding gene Chr6:133778784-133784883 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031170
protein coding gene Chr6:146378243-146401573 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031832
protein coding gene Chr6:132024515-132659450 (-)
PWK/PhJ MGP_PWKPhJ_G0030160
protein coding gene Chr6:125658260-125766984 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029989
protein coding gene Chr6:130071978-130492649 (-)
WSB/EiJ no annotation



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 2 genetic backgrounds
    6 phenotype references
Mice homozygous for a knock-out allele exhibit normal NK and T cell morphology and function.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 16636 NCBI Gene Model | MGI Sequence Detail 14237 C57BL/6J ±  kb
transcript NM_008463 RefSeq | MGI Sequence Detail 1155 C57BL/6  
polypeptide Q60652 UniProt | EBI | MGI Sequence Detail 266 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    Genomic 9
    cDNA 5
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-18730
References
more
  • Summaries
    All 35
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:10723 Yokoyama WM, et al., Chromosomal location of the Ly-49 (A1, YE1/48) multigene family. Genetic association with the NK 1.1 antigen. J Immunol. 1990 Oct 1;145(7):2353-8
  • Latest
    J:223451 Van Acker A, et al., Ly49E expression on CD8alphaalpha-expressing intestinal intraepithelial lymphocytes plays no detectable role in the development and progression of experimentally induced inflammatory bowel diseases. PLoS One. 2014;9(10):e110015

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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Funding Information
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory