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Tead1
Gene Detail
 Symbol
Name
ID
Tead1
TEA domain family member 1
MGI:101876
Synonyms 2610024B07Rik, B230114H05Rik, Gtrgeo5, mTEF-1, Tcf13, TEAD-1, TEF-1
Feature Type protein coding gene
Genetic Map
Chromosome 7
58.80 cM, cytoband F2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr7:112679318-112906807 bp, + strand
From VEGA annotation of GRCm38

  227490 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2418  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: transcriptional enhancer factor
Gene Tree: Tead1

Human
homologs
Human Homolog TEAD1, TEA domain family member 1 (SV40 transcriptional enhancer factor)
NCBI Gene ID 7003
neXtProt AC  NX_P28347
Human Synonyms  AA, NTEF-1, REF1, TCF13, TCF-13, TEAD-1, TEF-1
Human Chr (Location)  11p15.2; chr11:12674422-12944737 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human TEAD1
Alleles
and
phenotypes
All alleles(566) : Gene trapped(563) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions in this gene die between embryonic day 11 and 12.5. Abnormalities were seen in heart development.
 
Gene Ontology
(GO)
classifications
All GO classifications: (24 annotations)
Process embryonic heart tube morphogenesis, heart development, ...
Component cytoplasm, Golgi apparatus, ...
Function DNA binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (23 records)
Data Summary: Results (219)    Tissues (186)    Images (17)
Theiler Stages: 1, 2, 3, 4, 5, 10, 14, 15, 16, 17, 19, 21, 22, 23, 28
Assay TypeResults
Immunohistochemistry 3
RNA in situ 161
Northern blot 10
RT-PCR 45
cDNA source data(26)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(31) cDNA(27) Primer pair(4)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000036056 (Evidence)
Ensembl Gene ModelENSMUSG00000055320 (Evidence)
Entrez Gene21676 (Evidence)
DFCITC1583164, TC1584118, TC1598542, TC1598824, TC1630385
DoTSDT.40149941, DT.488856, DT.489389, DT.94154201, DT.94154214
NIA Mouse Gene IndexU008646, U008647
Consensus CDS ProjectCCDS52365.1, CCDS52366.1, CCDS52367.1
International Mouse Knockout Project StatusTead1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000036056 VEGA Gene Model | MGI Sequence Detail 227490 C57BL/6J ±  kb
transcript OTTMUST00000092575 VEGA | MGI Sequence Detail 9964 Not Applicable 
polypeptide OTTMUSP00000051199 VEGA | MGI Sequence Detail 436 Not Applicable 

For the selected sequences
All sequences(110) RefSeq(17) UniProt(12)
Polymorphisms SNPs within 2kb(2185 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000818 TEA/ATTS
InterPro IPR016361 Transcriptional enhancer factor
Protein Ontology PR:000016218 transcriptional enhancer factor TEF-1
References (Earliest) J:48110 Burglin TR, The TEA domain: a novel, highly conserved DNA-binding motif [letter]. Cell. 1991 Jul 12;66(1):11-2
(Latest) J:198500 Nakahara M, et al., Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice. Mamm Genome. 2013 Jun;24(5-6):228-39
All references(73)
Other
accession IDs
MGD-MRK-18702, MGD-MRK-18736, MGI:1917551, MGI:2444852

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory