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Srms Gene Detail
Summary
  • Symbol
    Srms
  • Name
    src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
  • Synonyms
    A230069J08Rik, srm
  • Feature Type
    protein coding gene
  • IDs
    MGI:101865
    NCBI Gene: 20811
Location & Maps
more
  • Sequence Map
    Chr2:181205562-181213185 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7624 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 103.62 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    SRMS, src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
  • Vertebrate Orthologs
    11
  • Human Ortholog
    SRMS, src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C20orf148, dJ697K14.1, PTK70, SRM
  • Links
    NCBI Gene ID: 6725
    neXtProt AC: NX_Q9H3Y6

  • Chr Location
    chr20:63539924-63547504 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
  • All Mutations and Alleles
    4
  • Gene trapped
    1
  • Targeted
    3
  • Incidental Mutations
Homozygous mice exhibit no detectable abnormalities.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016560 VEGA Gene Model | MGI Sequence Detail 7624 C57BL/6J ±  kb
transcript OTTMUST00000040036 VEGA | MGI Sequence Detail 2562 Not Applicable  
polypeptide OTTMUSP00000017864 VEGA | MGI Sequence Detail 507 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    72 from dbSNP Build 142
  • PCR
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 9
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-18690, MGI:2444916
References
more
  • Summaries
    All 29
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:20410 Kohmura N, et al., A novel nonreceptor tyrosine kinase, Srm: cloning and targeted disruption. Mol Cell Biol. 1994 Oct;14(10):6915-25
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory