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Gnb2l1
Gene Detail
 Symbol
Name
ID
Gnb2l1
guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1
MGI:101849
Synonyms GB-like, Gnb2-rs1, p205, Rack1
Feature Type protein coding gene
Genetic Map
Chromosome 11
28.77 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr11:48800332-48806434 bp, + strand
From VEGA annotation of GRCm38

  6103 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4446  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Gnb2l1

Human
homologs
Human Homolog GNB2L1, guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
NCBI Gene ID 10399
neXtProt AC  NX_P63244
Human Synonyms  Gnb2-rs1, H12.3, HLC-7, PIG21, RACK1
Human Chr (Location)  5q35.3; chr5:181236928-181243906 (-)  GRCh38
Alleles
and
phenotypes
All alleles(80) : Gene trapped(78) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (64 annotations)
Process activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, ...
Component cell projection, cytoplasm, ...
Function cysteine-type endopeptidase activator activity involved in apoptotic process, enzyme binding, ...
External Resources: FuncBase
Expression
Literature Summary: (9 records)
Data Summary: Results (34)    Tissues (25)    Images (5)
Theiler Stages: 21, 23, 25, 28
Assay TypeResults
RNA in situ 34
cDNA source data(1471)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(1477) cDNA(1474) Primer pair(2) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000005526 (Evidence)
Ensembl Gene ModelENSMUSG00000020372 (Evidence)
Entrez Gene14694 (Evidence)
UniGene5305
DFCITC1573653, TC1668305, TC1754707
NIA Mouse Gene IndexU012515
Consensus CDS ProjectCCDS24585.1
International Mouse Knockout Project StatusGnb2l1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005526 VEGA Gene Model | MGI Sequence Detail 6103 C57BL/6J ±  kb
transcript OTTMUST00000012289 VEGA | MGI Sequence Detail 1447 Not Applicable 
polypeptide OTTMUSP00000043241 VEGA | MGI Sequence Detail 317 Not Applicable 

For the selected sequences
All sequences(54) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(38 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR020472 G-protein beta WD-40 repeat
InterPro IPR001680 WD40 repeat
InterPro IPR019775 WD40 repeat, conserved site
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000008098 guanine nucleotide-binding protein subunit beta-2-like 1
References (Earliest) J:21457 Guillemot F, et al., Physical linkage of a guanine nucleotide-binding protein-related gene to the chicken major histocompatibility complex. Proc Natl Acad Sci U S A. 1989 Jun;86(12):4594-8
(Latest) J:179967 Zheng Y, et al., Interaction of protein inhibitor of activated STAT 2 (PIAS2) with receptor of activated C kinase 1, RACK1. FEBS Lett. 2012 Jan 20;586(2):122-6
All references(66)
Other
accession IDs
MGD-MRK-18672

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory