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Gnb2l1
Gene Detail
Symbol

Name
ID
Gnb2l1
guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1
MGI:101849
Synonyms
GB-like, Gnb2-rs1, p205, Rack1
Feature Type
protein coding gene
Genetic Map
Chromosome 11
28.77 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr11:48800332-48806434 bp, + strand
From VEGA annotation of GRCm38

  6103 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4446  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: GNB2L1
Gene Tree: Gnb2l1

Human
homologs
GNB2L1, guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 10399
neXtProt AC: NX_P63244

Human Synonyms: Gnb2-rs1, H12.3, HLC-7, PIG21, RACK1

Human Chr (Location): 5q35.3; chr5:181236928-181243906 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(80) : Gene trapped(78) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Gnb2l1 interacts with 65 markers (Mir17, Mir20a, Mir20b, ...)
Expression
Literature Summary: (9 records)
Data Summary: Results (34)    Tissues (25)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 34
cDNA source data(1471)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase gnb2l1 ; ZFIN gnb2l1    NEW 
Molecular
reagents
All nucleic(1477) cDNA(1474) Primer pair(2) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000005526 (Evidence)
Ensembl Gene Model ENSMUSG00000020372 (Evidence)
Entrez Gene 14694 (Evidence)
UniGene 5305
DFCI TC1573653, TC1668305, TC1754707
NIA Mouse Gene Index U012515
Consensus CDS Project CCDS24585.1
International Mouse Phenotyping Consortium Status Gnb2l1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005526 VEGA Gene Model | MGI Sequence Detail 6103 C57BL/6J ±  kb
transcript OTTMUST00000012289 VEGA | MGI Sequence Detail 1447 Not Applicable 
polypeptide OTTMUSP00000043241 VEGA | MGI Sequence Detail 317 Not Applicable 

For the selected sequences
All sequences(54) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(38 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR020472 G-protein beta WD-40 repeat
InterPro IPR001680 WD40 repeat
InterPro IPR019775 WD40 repeat, conserved site
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000008098 guanine nucleotide-binding protein subunit beta-2-like 1
References
(Earliest) J:21457 Guillemot F, et al., Physical linkage of a guanine nucleotide-binding protein-related gene to the chicken major histocompatibility complex. Proc Natl Acad Sci U S A. 1989 Jun;86(12):4594-8
(Latest) J:211328 Ma J, et al., DJ-1 interacts with RACK1 and protects neurons from oxidative-stress-induced apoptosis. Biochem J. 2014 Jun 20;
All references(66)
Other
accession IDs
MGD-MRK-18672

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory