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Ifi205 Gene Detail
Summary
  • Symbol
    Ifi205
  • Name
    interferon activated gene 205
  • Synonyms
    D3
  • Feature Type
    protein coding gene
  • IDs
    MGI:101847
    NCBI Gene: 226695
  • Gene Overview
    MyGene.info: IFI16
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:174011998-174031755 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 80.83 cM, cytoband H3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    238 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_101847
protein coding gene Chr1:174011998-174031810 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016819
protein coding gene Chr1:180010771-180068773 (-)
A/J no annotation
AKR/J MGP_AKRJ_G0016763
protein coding gene Chr1:177923319-177985185 (-)
BALB/cJ MGP_BALBcJ_G0016752
protein coding gene Chr1:172975367-173284825 (-)
C3H/HeJ MGP_C3HHeJ_G0016580
protein coding gene Chr1:178586587-178594835 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017218
protein coding gene Chr1:186068896-186105573 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014926
protein coding gene Chr1:164223603-164237109 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0016553
protein coding gene Chr1:192813118-192834675 (-)
DBA/2J MGP_DBA2J_G0016659
protein coding gene Chr1:171700812-171715007 (-)
FVB/NJ MGP_FVBNJ_G0016656
protein coding gene Chr1:169772749-169792713 (-)
LP/J MGP_LPJ_G0016734
protein coding gene Chr1:181094908-181163100 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016685
protein coding gene Chr1:199761661-199985787 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017253
protein coding gene Chr1:177789221-177813021 (-)
PWK/PhJ MGP_PWKPhJ_G0015948
protein coding gene Chr1:170776020-170789800 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0016219
protein coding gene Chr1:177590124-177945002 (-)



Homology
more
  • Human Ortholog
    IFI16, interferon gamma inducible protein 16
  • Vertebrate Orthologs
    16
  • Human Ortholog
    IFI16, interferon gamma inducible protein 16
    Orthology source: HomoloGene
  • Synonyms
    IFNGIP1, PYHIN2
  • Links
    NCBI Gene ID: 3428
    neXtProt AC: NX_Q16666
    UniProt: Q16666

  • Chr Location
    1q23.1; chr1:158999968-159055155 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 226695 NCBI Gene Model | MGI Sequence Detail 19758 C57BL/6J ±  kb
transcript NM_172648 RefSeq | MGI Sequence Detail 1613 C57BL/6  
polypeptide Q8CGE8 UniProt | EBI | MGI Sequence Detail 404 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    cDNA 19

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-18669
References
more
  • Summaries
    All 32
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:16675 Tannenbaum CS, et al., Characterization of lipopolysaccharide-induced macrophage gene expression. J Immunol. 1988 May 15;140(10):3640-5
  • Latest
    J:264978 Nakaya Y, et al., AIM2-Like Receptors Positively and Negatively Regulate the Interferon Response Induced by Cytosolic DNA. MBio. 2017 Jul 5;8(4)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory