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Elk1
Gene Detail
Symbol

Name
ID
Elk1
ELK1, member of ETS oncogene family
MGI:101833
Synonyms
Elk-1
Feature Type
protein coding gene
Genetic Map
Chromosome X
16.45 cM, cytoband A1-A3
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
ChrX:20933395-20950608 bp, - strand
From VEGA annotation of GRCm38

  17214 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3832  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog

HCOP human homology predictions: ELK1
Protein SuperFamily: elk-1 transforming protein
Gene Tree: Elk1

Human
homologs
ELK1, ELK1, member of ETS oncogene family
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 2002
neXtProt AC: NX_P19419

Human Chr (Location): Xp11.2; chrX:47635520-47650604 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(2) Targeted(6)
Interactions
Elk1 interacts with 276 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (32 annotations)
Process cell differentiation, cellular response to gamma radiation, ...
Component axon terminus, cytoplasm, ...
Function chromatin binding, core promoter binding, ...
External Resources: FuncBase
Expression
Literature Summary: (14 records)
Data Summary: Results (178)    Tissues (147)    Images (24)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 170
RT-PCR 8
cDNA source data(16)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase LOC100497609    NEW 
Molecular
reagents
All nucleic(22) Genomic(2) cDNA(17) Primer pair(2) Other(1)
Microarray probesets(9)
Other database
links
VEGA Gene Model OTTMUSG00000017185 (Evidence)
Ensembl Gene Model ENSMUSG00000009406 (Evidence)
Entrez Gene 13712 (Evidence)
DFCI TC1614712, TC1779205, TC1582345, TC1609238
NIA Mouse Gene Index U039301
Consensus CDS Project CCDS30048.1
International Mouse Phenotyping Consortium Status Elk1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017185 VEGA Gene Model | MGI Sequence Detail 17214 C57BL/6J ±  kb
transcript OTTMUST00000041618 VEGA | MGI Sequence Detail 3548 Not Applicable 
polypeptide OTTMUSP00000018693 VEGA | MGI Sequence Detail 429 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(2) UniProt(4)
Polymorphisms
RFLP(1) : SNPs within 2kb(31 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000418 Ets domain
InterPro IPR011991 Winged helix-turn-helix DNA-binding domain
Protein Ontology PR:000007025 ETS domain-containing protein Elk-1
References
(Earliest) J:19206 Giovane A, et al., Net, a new ets transcription factor that is activated by Ras. Genes Dev. 1994 Jul 1;8(13):1502-13
(Latest) J:219394 Boroviak T, et al., The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification. Nat Cell Biol. 2014 Jun;16(6):516-28
All references(68)
Other
accession IDs
MGD-MRK-18654

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory