About   Help   FAQ
Dppa5a Gene Detail
Summary
  • Symbol
    Dppa5a
  • Name
    developmental pluripotency associated 5A
  • Synonyms
    Dppa5, ecat2, Esg1
  • Feature Type
    protein coding gene
  • IDs
    MGI:101800
    NCBI Gene: 434423
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:78367052-78368177 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 43.65 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    19 from dbSNP Build 142
  • Strain Annotations
    13
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_101800
protein coding gene Chr9:78367052-78368199 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035062
protein coding gene Chr9:78737324-78738281 (+)
A/J MGP_AJ_G0035047
protein coding gene Chr9:76141334-76148534 (-)
AKR/J MGP_AKRJ_G0034975
protein coding gene Chr9:77949614-77950956 (-)
BALB/cJ MGP_BALBcJ_G0035035
protein coding gene Chr9:75800748-75803746 (-)
C3H/HeJ MGP_C3HHeJ_G0034747
protein coding gene Chr9:78467080-78468847 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035556
protein coding gene Chr9:80987494-80989792 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032465
protein coding gene Chr9:75381069-75382177 (+)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0034720
protein coding gene Chr9:83856019-83856832 (-)
DBA/2J MGP_DBA2J_G0034878
protein coding gene Chr9:75786631-75787435 (-)
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0034863
protein coding gene Chr9:85032395-85033119 (-)
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0033768
protein coding gene Chr9:75932107-75948984 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033605
protein coding gene Chr9:78309048-78309582 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    DPPA5, developmental pluripotency associated 5
  • Vertebrate Orthologs
    5
  • Human Ortholog
    DPPA5, developmental pluripotency associated 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ESG1
  • Links
    NCBI Gene ID: 340168
    neXtProt AC: NX_A6NC42
    UniProt: A6NC42

  • Chr Location
    6q13; chr6:73353062-73354276 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
  • All Mutations and Alleles
    53
  • Chemically induced (other)
    1
  • Gene trapped
    49
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Dppa5a
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
Homozygous null mice exhibit normal development and fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000060461 Ensembl Gene Model | MGI Sequence Detail 1126 C57BL/6J ±  kb
transcript ENSMUST00000071991 Ensembl | MGI Sequence Detail 619 Not Applicable  
polypeptide ENSMUSP00000071881 Ensembl | MGI Sequence Detail 118 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 23
    Genomic 1
    cDNA 15
    Primer pair 4
    Other 3

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-18610, MGI:2142955, MGI:2157526
References
more
  • Summaries
    All 53
    Developmental Gene Expression 18
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:12013 Russell LB, Definition of functional units in a small chromosomal segment of the mouse and its use in interpreting the nature of radiation-induced mutations. Mutat Res. 1971 Jan;11(1):107-23
  • Latest
    J:236825 Langer D, et al., Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation. Nat Commun. 2016 Mar 30;7:11063

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/15/2019
MGI 6.14
The Jackson Laboratory