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Cisd3 Gene Detail
Summary
  • Symbol
    Cisd3
  • Name
    CDGSH iron sulfur domain 3
  • Synonyms
    Mel13
  • Feature Type
    protein coding gene
  • IDs
    MGI:101788
    NCBI Gene: 217149
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr11:97685826-97688621 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 61.06 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    19 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_101788
protein coding gene Chr11:97685465-97688625 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026812
protein coding gene Chr2:168197047-168197691 (-)
A/J MGP_AJ_G0026778
protein coding gene Chr2:161453330-161454174 (-)
AKR/J MGP_AKRJ_G0026749
protein coding gene Chr2:166209823-166210737 (-)
BALB/cJ MGP_BALBcJ_G0026787
protein coding gene Chr2:161772366-161772970 (-)
C3H/HeJ MGP_C3HHeJ_G0026529
protein coding gene Chr2:166559128-166559782 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019429
protein coding gene Chr11:103231880-103235249 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017060
protein coding gene Chr11:93463088-93465809 (+)
CAST/EiJ MGP_CASTEiJ_G0018344
protein coding gene Chr11:99976047-99978844 (+)
CBA/J MGP_CBAJ_G0026506
protein coding gene Chr2:179396010-179396634 (-)
DBA/2J MGP_DBA2J_G0026644
protein coding gene Chr2:160620794-160621388 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0026747
protein coding gene Chr2:168346464-168347088 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026632
protein coding gene Chr2:183087786-183088340 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019469
protein coding gene Chr11:99291043-99294686 (+)
PWK/PhJ MGP_PWKPhJ_G0018116
protein coding gene Chr11:96544995-96547895 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017906
protein coding gene Chr11:99009346-99012075 (+)
WSB/EiJ MGP_WSBEiJ_G0018394
protein coding gene Chr11:99198258-99202455 (+)



Homology
more
  • Human Ortholog
    CISD3, CDGSH iron sulfur domain 3
  • Vertebrate Orthologs
    6
  • Human Ortholog
    CISD3, CDGSH iron sulfur domain 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    Miner2, MiNT
  • Links
    NCBI Gene ID: 284106
    neXtProt AC: NX_P0C7P0
    UniProt: P0C7P0

  • Chr Location
    17q12; chr17:38730257-38735605 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000078695 Ensembl Gene Model | MGI Sequence Detail 2796 C57BL/6J ±  kb
transcript ENSMUST00000107583 Ensembl | MGI Sequence Detail 737 Not Applicable  
polypeptide ENSMUSP00000103209 Ensembl | MGI Sequence Detail 137 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000030840 CDGSH iron-sulfur domain-containing protein 3, mitochondrial
  • InterPro Domains
    IPR018967 Iron sulphur-containing domain, CDGSH-type
Molecular
Reagents
less
  • All nucleic 48
    Genomic 1
    cDNA 47

    Microarray probesets 1
Other
Accession IDs
less
MGD-MRK-18596
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:15805 Haupt Y, et al., Nucleotide sequence of bup, an upstream gene in the bmi-1 proviral insertion locus. Mol Biol Rep. 1992 Nov;17(1):17-20
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/11/2019
MGI 6.14
The Jackson Laboratory