mt-Nd1
Gene Detail

Symbol Name ID

mt-Nd1 mitochondrially encoded NADH dehydrogenase 1 MGI:101787

Synonyms

0610040O15Rik, ND1, protein 1, URF1

Feature Type

protein coding gene

Genetic Map

Chromosome MT
Syntenic

Sequence Map

ChrMT:2751-3707 bp, + strand From Ensembl annotation of GRCm38   957 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:5011  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: NADH:quinone oxidoreductase (complex I), subunit 1/[NiFe]-hydrogenase-3-type complex, membrane subunit C/D/J
Gene Tree: mt-Nd1

Human homologs

Human Homolog		ND1, NADH dehydrogenase, subunit 1 (complex I)
NCBI Gene ID		4535
neXtProt AC		NX_P03886
Human Synonyms		MTND1
Human Chr (Location)		MT
Disease Associations		(2) Diseases Associated with Human ND1

Alleles and phenotypes

All alleles(2) : Gene trapped(2)

Gene Ontology (GO) classifications

All GO classifications: (16 annotations)

Process	electron transport chain, oxidation-reduction process, ...
Component	dendrite, integral to membrane, ...
Function	NADH dehydrogenase (ubiquinone) activity, oxidoreductase activity

External Resources: FuncBase

Expression

cDNA source data(6)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(58) cDNA(6) Other(52)
Microarray probesets(1)

Other database links

Ensembl Gene Model	ENSMUSG00000064341 (Evidence)
Entrez Gene	17716
NIA Mouse Gene Index	U337417
EC	1.6.5.3
International Mouse Knockout Project Status	mt-Nd1

Sequences

Length	Strain/Species
genomic	ENSMUSG00000064341	Ensembl Gene Model | MGI Sequence Detail	957	C57BL/6J
transcript	ENSMUST00000082392	Ensembl | MGI Sequence Detail	957	Not Applicable
polypeptide	ENSMUSP00000080991	Ensembl | MGI Sequence Detail	318	Not Applicable

All sequences(53) RefSeq(1) UniProt(4)

Protein-related information

Resource	ID	Description
InterPro	IPR018086	NADH:ubiquinone oxidoreductase, subunit 1, conserved site
InterPro	IPR001694	NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H

References

(Earliest) J:22484 Bibb MJ, et al., Sequence and gene organization of mouse mitochondrial DNA. Cell. 1981 Oct;26(2 Pt 2):167-80
(Latest) J:162436 Gao X, et al., Mitochondrial dysfunction may explain the cardiomyopathy of chronic iron overload. Free Radic Biol Med. 2010 Aug 1;49(3):401-7
All references(29)

Other accession IDs

MGD-MRK-18595, MGI:1925550