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Sntb1
Gene Detail
 Symbol
Name
ID
Sntb1
syntrophin, basic 1
MGI:101781
Synonyms 59-1 DAP, beta1-Syntrophin
Feature Type protein coding gene
Genetic Map
Chromosome 15
22.14 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr15:55638843-55906949 bp, - strand
From VEGA annotation of GRCm38

  268107 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9618  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Sntb1

Human
homologs
Human Homolog SNTB1, syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
NCBI Gene ID 6641
neXtProt AC  NX_Q13884
Human Synonyms  59-DAP, A1B, BSYN2, DAPA1B, SNT2, SNT2B1, TIP-43
Human Chr (Location)  8q23-q24; chr8:120535745-120813061 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(2) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Sntb1 interacts with 91 markers (Mir16-2, Mir18, Mir18b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Component cell junction, cytoplasm, ...
Function actin binding, calmodulin binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (3)    Tissues (1)   
Theiler Stages: 21
Assay TypeResults
RT-PCR 3
cDNA source data(4)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(5) cDNA(4) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000023696 (Evidence)
Ensembl Gene ModelENSMUSG00000060429 (Evidence)
Entrez Gene20649 (Evidence)
DFCITC1585166
NIA Mouse Gene IndexU072806
Consensus CDS ProjectCCDS27479.1
International Mouse Knockout Project StatusSntb1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023696 VEGA Gene Model | MGI Sequence Detail 268107 C57BL/6J ±  kb
transcript OTTMUST00000057865 VEGA | MGI Sequence Detail 2464 Not Applicable 
polypeptide OTTMUSP00000027977 VEGA | MGI Sequence Detail 537 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(4) UniProt(1)
Polymorphisms SNPs within 2kb(1178 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001478 PDZ domain
InterPro IPR001849 Pleckstrin homology domain
InterPro IPR011993 Pleckstrin homology-like domain
InterPro IPR015482 Syntrophin
Protein Ontology PR:000015351 beta-1-syntrophin
References (Earliest) J:16941 Yang B, et al., Heterogeneity of the 59-kDa dystrophin-associated protein revealed by cDNA cloning and expression. J Biol Chem. 1994 Feb 25;269(8):6040-4
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(34)
Other
accession IDs
MGD-MRK-18589

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory