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Sntb1 Gene Detail
Summary
  • Symbol
    Sntb1
  • Name
    syntrophin, basic 1
  • Synonyms
    59-1 DAP, beta1-Syntrophin
  • Feature Type
    protein coding gene
  • IDs
    MGI:101781
    NCBI Gene: 20649
  • Gene Overview
    MyGene.info: SNTB1
Location & Maps
more
  • Sequence Map
    Chr15:55638843-55906949 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      268107 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 22.14 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    SNTB1, syntrophin beta 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SNTB1, syntrophin beta 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    59-DAP, A1B, BSYN2, DAPA1B, SNT2, SNT2B1, TIP-43
  • Links
    NCBI Gene ID: 6641
    neXtProt AC: NX_Q13884

  • Chr Location
    8q23-q24; chr8:120535745-120812069 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 9618
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: SNTB1
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    3
  • Gene trapped
    2
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    4 involving Sntb1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023696 VEGA Gene Model | MGI Sequence Detail 268107 C57BL/6J ±  kb
transcript OTTMUST00000057865 VEGA | MGI Sequence Detail 2464 Not Applicable  
polypeptide OTTMUSP00000027977 VEGA | MGI Sequence Detail 537 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1174 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 4
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-18589
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 7
    Phenotypes 15
  • Earliest
    J:16941 Yang B, et al., Heterogeneity of the 59-kDa dystrophin-associated protein revealed by cDNA cloning and expression. J Biol Chem. 1994 Feb 25;269(8):6040-4
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory