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Dcaf8l Gene Detail
Summary
  • Symbol
    Dcaf8l
  • Name
    DDB1 and CUL4 associated factor 8 like
  • Synonyms
    PC231, PC326, Pet2, Pex3
  • Feature Type
    protein coding gene
  • IDs
    MGI:101758
    NCBI Gene: 18630
  • Alliance
Location &
Maps
more
  • Sequence Map
    ChrX:88447454-88453295 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 39.95 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    20 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_101758
protein coding gene ChrX:88447454-88453295 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035894
protein coding gene ChrX:85653754-85659021 (-)
A/J MGP_AJ_G0035880
protein coding gene ChrX:85723353-85729581 (-)
AKR/J MGP_AKRJ_G0035798
protein coding gene ChrX:87930873-87936435 (-)
BALB/cJ MGP_BALBcJ_G0035860
protein coding gene ChrX:84421947-84432679 (-)
C3H/HeJ MGP_C3HHeJ_G0035571
protein coding gene ChrX:85866809-85873348 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036391
protein coding gene ChrX:88221769-88228075 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033223
protein coding gene ChrX:84271317-84276537 (-)
CAST/EiJ MGP_CASTEiJ_G0034859
protein coding gene ChrX:70780812-70786140 (-)
CBA/J MGP_CBAJ_G0035546
protein coding gene ChrX:90683627-90691537 (-)
DBA/2J MGP_DBA2J_G0035700
protein coding gene ChrX:85020913-85027111 (-)
FVB/NJ MGP_FVBNJ_G0035640
protein coding gene ChrX:84438232-84443500 (-)
LP/J MGP_LPJ_G0035790
protein coding gene ChrX:86384787-86397178 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035676
protein coding gene ChrX:94755843-94762773 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036418
protein coding gene ChrX:85298935-85304201 (-)
PWK/PhJ MGP_PWKPhJ_G0034557
protein coding gene ChrX:68761107-68766425 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034388
protein coding gene ChrX:71904369-71911593 (-)
WSB/EiJ MGP_WSBEiJ_G0034998
protein coding gene ChrX:84199775-84205042 (-)



Homology
more
  • Human Ortholog
    DCAF8L1, DDB1 and CUL4 associated factor 8 like 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DCAF8L1, DDB1 and CUL4 associated factor 8 like 1
  • Synonyms
    WDR42B
  • Links
    NCBI Gene ID: 139425
    neXtProt AC: NX_A6NGE4
    UniProt: A6NGE4

  • Chr Location
    Xp21.3; chrX:27977993-27981449 (-)  GRCh38.p7

  • Human Ortholog
    DCAF8L2, DDB1 and CUL4 associated factor 8 like 2
  • Synonyms
    WDR42C
  • Links
    NCBI Gene ID: 347442
    UniProt: P0C7V8

  • Chr Location
    Xp21.3; chrX:27746809-27748821 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 18630 NCBI Gene Model | MGI Sequence Detail 5842 C57BL/6J ±  kb
transcript NM_008821 RefSeq | MGI Sequence Detail 4182 C57BL/6  
polypeptide NP_032847 RefSeq | MGI Sequence Detail 747 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR045151 DDB1- and CUL4-associated factor 8-like
    IPR001680 WD40 repeat
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Molecular
Reagents
less
  • All nucleic 4
    Genomic 1
    cDNA 3

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-18564
References
more
  • Summaries
    All 16
    Gene Ontology 1
  • Earliest
    J:10429 Timblin C, et al., Application for PCR technology to subtractive cDNA cloning: identification of genes expressed specifically in murine plasmacytoma cells. Nucleic Acids Res. 1990 Mar 25;18(6):1587-93
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/22/2022
MGI 6.21
The Jackson Laboratory