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Gcnt1 Gene Detail
 Symbol
Name
ID
Gcnt1
glucosaminyl (N-acetyl) transferase 1, core 2
MGI:95676


Nomenclature History
Synonyms 5630400D21Rik, beta-1, 6-N-acetylglucosaminyltransferase, C2 GlcNAcT, IGnT
Genetic Map
Chromosome 19
17.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 3)

Sequence Map
Chr19:17403165-17431107 bp, - strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Gcnt1 ± 2 cM)
TreeFam: TF315534
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000038843 Ensembl Gene Model | MGI Sequence Detail 27943 C57BL/6J ± Kb
transcript NM_173442 RefSeq | MGI Sequence Detail 4624 C57BL/6
polypeptide Q09324 UniProt | EBI | MGI Sequence Detail 428 Not Applicable
For the selected sequences
All sequences(31)
Alleles
and
phenotypes
All alleles(13) : Targeted, knock-out(1) Targeted, other(1) Gene trapped(11)
Mice homozygous for disruptions in this allele display a grossly normal phenotype and are fertile. There are abnormalities in white blood cell counts and in inflammatory response however.
Polymorphisms RFLP(2) SNPs within 2kb(185 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Component Golgi apparatus, integral to membrane...
Function acetylglucosaminyltransferase activity, beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity...
External Resources: FuncBase
Expression Literature Summary: (2 records)
Data Summary: Assays (1)    Results (1)    Tissues (1)    Images (1)
Theiler Stages: 22
  Assay Type Assays   Results
      RNA in situ 1   1
cDNA source data(64)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents
All nucleic(71) Genomic(5) cDNA(66)
Microarray probesets(2)
Other database
links
EC 2.4.1.102
Ensembl Gene Model ENSMUSG00000038843
DoTS DT.101337716, DT.101379826, DT.102557417, DT.489086, DT.97360437, DT.97393249
Consensus CDS Project CCDS29687.1
UniGene 244825
PDB 2GAK, 2GAM
DFCI TC1576333
NIA Mouse Gene Index U038894
Entrez Gene 14537
International Mouse Knockout Project Status Gcnt1
Protein
domains
InterPro ID Description
IPR003406 Glycosyl transferase, family 14
Graphical View of Protein Domain Structure
References
(Earliest) J:11178 Spies T et al., "Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporter [see comments]" Nature 1991 May 23;351(6324):323-4
(Latest) J:149909 Stone EL et al., "Glycosyltransferase function in core 2-type protein O glycosylation." Mol Cell Biol 2009 Jul;29(13):3770-82
All references(31)
Other
accession IDs
MGD-MRK-10022, MGI:1918694

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/06/2010
MGI_4.32
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The Jackson Laboratory