Symbol
Name
ID
|
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Synonyms
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Lyb-8, Lyb8
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Genetic Map
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Sequence Map
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Mammalian
homology
|
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Sequences
|
All sequences(58)
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Alleles
and
phenotypes
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All alleles(6) :
Targeted, knock-out(5)
Targeted, other(1)
| Homozygous null mice have reduced mature B cell numbers with altered proliferation kinetics and reduced antibody production to T cell independent antigens. |
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Polymorphisms
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RFLP(5)
SNPs within 2kb(163 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
|
Literature Summary: (1 records)
Data Summary:
Assays (1)
Results (46)
Tissues (45)
Images (1)
Theiler Stages: 23,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
1 |
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46 |
cDNA source data(23)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(27)
Genomic(3)
cDNA(23)
Primer pair(1)
Microarray probesets(3)
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Other database
links
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| Ensembl Gene Model |
ENSMUSG00000030577 |
| DoTS |
DT.101332297, DT.101360519, DT.101368681, DT.101387446, DT.101735692, DT.110994805, DT.110994813, DT.488385, DT.91339727, DT.91339728, DT.91339730, DT.91339731, DT.91339732, DT.91339734, DT.99858762 |
| Consensus CDS Project |
CCDS21114.1 |
| UniGene |
260994 |
| DFCI |
TC1581015, TC1588258, TC1623396, TC1660438, TC1692534, TC1694392 |
| Entrez Gene |
12483 |
| International Mouse Knockout Project Status |
Cd22 |
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Protein
domains
|
Graphical View
of Protein Domain Structure
|
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References
|
(Earliest)
J:6945
Symington FW et al.,
"Lyb-8.2: A new B cell antigen defined and characterized with a monoclonal antibody."
Immunogenetics 1982;16(5):381-91
(Latest)
J:150309
Gross AJ et al.,
"Developmental acquisition of the Lyn-CD22-SHP-1 inhibitory pathway promotes B cell tolerance."
J Immunol 2009 May 1;182(9):5382-92
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All references(63)
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Other
accession IDs
|
MGD-MRK-12060, MGD-MRK-12066, MGD-MRK-1839
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Analysis Tools
MGI BioMart
