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St8sia6 Gene Detail
 Symbol
Name
ID
St8sia6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
MGI:2386797

Nomenclature History
Synonyms 1700007J08Rik, Siat8f, ST8Sia VI
Genetic Map
Chromosome 2
Syntenic
 
Mapping data( 3)
Sequence Map
Chr2:13572647-13715435 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: sialyltransferase
TreeFam: TF323961
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000011299 VEGA Gene Model | MGI Sequence Detail 142789 C57BL/6J ± Kb
transcript NM_145838 RefSeq | MGI Sequence Detail 3166 -
polypeptide Q8K4T1 UniProt | EBI | MGI Sequence Detail 398 Not Applicable
For the selected sequences
All sequences(28)
Alleles
and
phenotypes 		All alleles(1) : Targeted, knock-out(1)
Polymorphisms SNPs within 2kb(495 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process carbohydrate biosynthetic process, glycolipid biosynthetic process...
Component Golgi apparatus, integral to Golgi membrane...
Function sialyltransferase activity, transferase activity...
External Resources: FuncBase
Expression cDNA source data(7)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(11) Genomic(2) cDNA(9)
Microarray probesets(1)
Other database
links
Ensembl Gene Model ENSMUSG00000003418
DoTS DT.101723819, DT.55152706
Consensus CDS Project CCDS15697.1
DFCI TC1582378, TC1664348
NIA Mouse Gene Index U022300, U265727
Entrez Gene 241230
VEGA Gene Model OTTMUSG00000011299
International Mouse Knockout Project Status St8sia6
Protein
domains
InterPro ID Description
IPR001675 Glycosyl transferase, family 29
IPR012163 Sialyltransferase
Graphical View of Protein Domain Structure
References
(Earliest) J:65060 Kawai J et al., "Functional annotation of a full-length mouse cDNA collection." Nature 2001 Feb 8;409(6821):685-90
(Latest) J:117561 Teintenier-Lelievre M et al., "Molecular cloning and expression of a human hST8Sia VI (alpha2,8-sialyltransferase) responsible for the synthesis of the diSia motif on O-glycosylproteins." Biochem J 2005 Dec 15;392(Pt 3):665-74
All references(7)
Other
accession IDs 		MGI:1916566, MGI:2138880, MGI:2139109
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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