About   Help   FAQ
Tour our new Quick Search
Cd207 Gene Detail
 Symbol
Name
ID
Cd207
CD207 antigen
MGI:2180021

Nomenclature History
Synonyms Langerin
Genetic Map
Chromosome 6
cytoband D1-D2
 
Mapping data( 1)
Sequence Map
Chr6:83621209-83627851 bp, - strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; rat    (Mammalian Orthology)
TreeFam: TF333341
Sequences
Representative Sequences Length Strain/Species Flank
genomic 246278 NCBI Gene Model | MGI Sequence Detail 6643 C57BL/6J ± Kb
transcript NM_144943 RefSeq | MGI Sequence Detail 1565 -
polypeptide Q8VBX4 UniProt | EBI | MGI Sequence Detail 331 Not Applicable
For the selected sequences
All sequences(15)
Alleles
and
phenotypes 		All alleles(6) : Targeted, knock-out(3) Targeted, other(3)
Polymorphisms SNPs within 2kb(78 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Component integral to membrane, integral to plasma membrane...
Function binding, sugar binding...
External Resources: FuncBase
Expression cDNA source data(3)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(4) cDNA(3) Other(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000034783
DoTS DT.482291
Consensus CDS Project CCDS39534.1
UniGene 136079
DFCI TC1589657
NIA Mouse Gene Index U027535
Entrez Gene 246278
International Mouse Knockout Project Status Cd207
Protein
domains
InterPro ID Description
IPR001304 C-type lectin
IPR016186 C-type lectin-like
IPR016187 C-type lectin fold
IPR018378 C-type lectin, conserved site
Graphical View of Protein Domain Structure
References
(Earliest) J:59970 Valladeau J et al., "Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules." Immunity 2000 Jan;12(1):71-81
(Latest) J:155680 Chorro L et al., "Langerhans cell (LC) proliferation mediates neonatal development, homeostasis, and inflammation-associated expansion of the epidermal LC network." J Exp Med 2009 Dec 21;206(13):3089-100
All references(22)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
Web browser compatibility 		The Jackson Laboratory