Symbol
Name
ID
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Synonyms
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1700020N17Rik, 2310001G17Rik, 2900054O13Rik, 4930445M19Rik, 5730402G09Rik, nmf243, Nna1
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(65)
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Alleles
and
phenotypes
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All alleles(17) :
Gene trapped(6)
Transgenic(1)
Spontaneous(6)
Chemically induced(4)
| Homozygotes show moderate ataxia due to degeneration of Purkinje cells of the cerebellum. Also, there is gradual degeneration of retina photoreceptor cells, olfactory bulb mitral cells and some thalamic neurons. Males have abnormal sperm and are sterile. |
Phenotype Images (3)
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Polymorphisms
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RFLP(1)
SNPs within 2kb(709 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (1 records)
Data Summary:
Assays (2)
Results (17)
Tissues (11)
Theiler Stages: 22,25,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
1 |
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12 |
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RNA in situ |
1 |
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5 |
cDNA source data(15)
External Resources:
Allen Brain Atlas
GENSAT
GEO
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Molecular
reagents
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All nucleic(21)
Genomic(1)
cDNA(17)
Primer pair(3)
Microarray probesets(3)
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Other database
links
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| Ensembl Gene Model |
ENSMUSG00000021557 |
| DoTS |
DT.101323270, DT.101353189, DT.101384842, DT.101703215, DT.101736879, DT.110974931, DT.527005, DT.55232398, DT.91429199, DT.91588723, DT.94158776, DT.94266764, DT.94273792, DT.97414227, DT.99848187 |
| DFCI |
TC1578973, TC1586050, TC1593599, TC1603506, TC1606364, TC1610931, TC1636438, TC1636588, TC1670366, TC1701767, TC1714363, TC1750777 |
| NIA Mouse Gene Index |
U034857, U034858 |
| Entrez Gene |
67269 |
| International Mouse Knockout Project Status |
Agtpbp1 |
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Protein
domains
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| InterPro ID |
Description |
| IPR000834 |
Peptidase M14, carboxypeptidase A |
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:5597
Mullen RJ et al.,
"Two types of retinal degeneration in cerebellar mutant mice."
Nature 1975 Dec 11;258(5535):528-30
(Latest)
J:146470
Matsuda K et al.,
"Cbln1 binds to specific postsynaptic sites at parallel fiber-Purkinje cell synapses in the cerebellum."
Eur J Neurosci 2009 Feb;29(4):707-17
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All references(107)
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Other
accession IDs
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MGD-MRK-13173, MGI:1914519, MGI:1916623, MGI:1921986, MGI:1922111, MGI:1923828, MGI:2145471, MGI:97500
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