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Cd209a Gene Detail
 Symbol
Name
ID
Cd209a
CD209a antigen
MGI:2157942

Nomenclature History
Synonyms CD209, CIRE, DC-SIGN, DC-SIGN1, Dcsign, SIGNR5
Genetic Map
Chromosome 8
Syntenic
 
Mapping data( 1)
Sequence Map
Chr8:3743397-3748930 bp, - strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; rat    (Mammalian Orthology)
TreeFam: TF333341
Sequences
Representative Sequences Length Strain/Species Flank
genomic 170786 NCBI Gene Model | MGI Sequence Detail 5534 C57BL/6J ± Kb
transcript NM_133238 RefSeq | MGI Sequence Detail 1484 -
polypeptide Q91ZX1 UniProt | EBI | MGI Sequence Detail 238 Not Applicable
For the selected sequences
All sequences(20)
Alleles
and
phenotypes 		All alleles(3) : Targeted, knock-out(3)
Mice homozygous for a knock-out allele exhibit normal susceptibility to bacterial infection.
Polymorphisms SNPs within 2kb(49 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process endocytosis
Component integral to membrane, membrane...
Function binding, calcium ion binding...
External Resources: FuncBase
Expression cDNA source data(5)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(7) Genomic(2) cDNA(5)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000031494
DoTS DT.110868907, DT.97342134
Consensus CDS Project CCDS22073.1
UniGene 32510
DFCI TC1584413
NIA Mouse Gene Index U029543
Entrez Gene 170786
International Mouse Knockout Project Status Cd209a
Protein
domains
InterPro ID Description
IPR001304 C-type lectin
IPR002353 Type II antifreeze protein
IPR016186 C-type lectin-like
IPR016187 C-type lectin fold
IPR018378 C-type lectin, conserved site
Graphical View of Protein Domain Structure
References
(Earliest) J:72165 Park CG et al., "Five mouse homologues of the human dendritic cell C-type lectin, DC-SIGN." Int Immunol 2001 Oct;13(10):1283-90
(Latest) J:153503 Tanne A et al., "A murine DC-SIGN homologue contributes to early host defense against Mycobacterium tuberculosis." J Exp Med 2009 Sep 28;206(10):2205-20
All references(10)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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