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Pofut2 Gene Detail
 Symbol
Name
ID
Pofut2
protein O-fucosyltransferase 2
MGI:1916863

Nomenclature History
Synonyms 2310011G23Rik, FUT13, MGC:6943
Genetic Map
Chromosome 10
Syntenic
 
Mapping data( 2)
Sequence Map
Chr10:76722051-76732314 bp, + strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; rat    (Mammalian Orthology)
TreeFam: TF314337
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000020260 Ensembl Gene Model | MGI Sequence Detail 10264 C57BL/6J ± Kb
transcript NM_030262 RefSeq | MGI Sequence Detail 2219 C57BL/6
polypeptide Q8VHI3 UniProt | EBI | MGI Sequence Detail 429 Not Applicable
For the selected sequences
All sequences(32)
Alleles
and
phenotypes 		All alleles(7) : Gene trapped(7)
Homozygous mutation of this gene results in lethality before weaning.
Polymorphisms SNPs within 2kb(52 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process carbohydrate metabolic process, fucose metabolic process...
Component endoplasmic reticulum
Function peptide-O-fucosyltransferase activity, transferase activity...
External Resources: FuncBase
Expression Literature Summary: (4 records)
Data Summary: Assays (6)    Results (116)    Tissues (66)    Images (5)
Theiler Stages: 13,15,17,20,22,23,26,28
  Assay Type Assays   Results
      RT-PCR 2   18
      RNA in situ 4   98
cDNA source data(90)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(94) cDNA(92) Primer pair(2)
Microarray probesets(3)
Other database
links
EC 2.4.1.221
Ensembl Gene Model ENSMUSG00000020260
DoTS DT.110624058, DT.533532
Consensus CDS Project CCDS23954.1
UniGene 203556
DFCI TC1572825
NIA Mouse Gene Index U011684
Entrez Gene 80294
International Mouse Knockout Project Status Pofut2
Protein
domains
InterPro ID Description
IPR019378 GDP-fucose protein O-fucosyltransferase
Graphical View of Protein Domain Structure
References
(Earliest) J:93290 Araki K et al., "Exchangeable gene trap using the Cre/mutated lox system." Cell Mol Biol (Noisy-le-grand) 1999 Jul;45(5):737-50
(Latest) J:142424 Kim ML et al., "O-fucosylation of muscle agrin determines its ability to cluster acetylcholine receptors." Mol Cell Neurosci 2008 Nov;39(3):452-64
All references(14)
Other
accession IDs 		MGI:1933140, MGI:2143552
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
Web browser compatibility 		The Jackson Laboratory