Symbol
Name
ID
|
|
|
Synonyms
|
1810030I22Rik, mSIGNR1, SIGNR1
|
|
Genetic Map
|
|
Chromosome 8
|
cytoband A1.2-A1.3
|
|
|
|
Mapping data(
4)
|
|
|
|
Sequence Map
|
|
Mammalian homology
|
|
|
Sequences
|
All sequences(45)
|
Alleles and phenotypes
|
All alleles(3) :
Targeted, knock-out(3)
| Homozygous mutants are more susceptible to S. pneumoniae infection and fail to clear the bacteria from the circulation. Marginal zone and peritoneal macrophages are impaired in recognizing the bacteria. |
|
|
Polymorphisms
|
SNPs within 2kb(65 from dbSNP Build 128)
|
Gene Ontology (GO) classifications
|
|
|
Expression
|
cDNA source data(14)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
|
Molecular reagents
|
All nucleic(17)
Genomic(1)
cDNA(14)
Other(2)
Microarray probesets(2)
|
Other database links
|
|
Protein domains
|
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:65060
Kawai J et al.,
"Functional annotation of a full-length mouse cDNA collection."
Nature 2001 Feb 8;409(6821):685-90
(Latest)
J:156365
Srivastava V et al.,
"Toll-like receptor 2 and DC-SIGNR1 differentially regulate suppressors of cytokine signaling 1 in dendritic cells during Mycobacterium tuberculosis infection."
J Biol Chem 2009 Sep 18;284(38):25532-41
|
All references(18)
|