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Cd209b Gene Detail
 Symbol
Name
ID
Cd209b
CD209b antigen
MGI:1916415


Nomenclature History
Synonyms 1810030I22Rik, mSIGNR1, SIGNR1
Genetic Map
Chromosome 8
cytoband A1.2-A1.3
 
Mapping data( 4)
Sequence Map
Chr8:3917657-3926814 bp, - strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
rat    (Mammalian Orthology)
TreeFam: TF333341
Sequences
Representative Sequences Length Strain/Species Flank
genomic 69165 NCBI Gene Model | MGI Sequence Detail 9158 C57BL/6J ± Kb
transcript NM_026972 RefSeq | MGI Sequence Detail 2020 C57BL/6
polypeptide Q8CJ91 UniProt | EBI | MGI Sequence Detail 325 Not Applicable
For the selected sequences
All sequences(45)
Alleles
and
phenotypes
All alleles(3) : Targeted, knock-out(3)
Homozygous mutants are more susceptible to S. pneumoniae infection and fail to clear the bacteria from the circulation. Marginal zone and peritoneal macrophages are impaired in recognizing the bacteria.
Polymorphisms SNPs within 2kb(65 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(17)
Process detection of bacterium, detection of yeast...
Component external side of plasma membrane, integral to membrane...
Function binding, calcium ion binding...
External Resources: MouseFunc
Expression cDNA source data(14)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(15) Genomic(1) cDNA(14)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000065987
DoTS DT.101291976, DT.97388549, DT.99773330, DT.99773355
UniGene 175163
DFCI TC1583834, TC1594382
NIA Mouse Gene Index U102797
Entrez Gene 69165
International Mouse Knockout Project Status Cd209b
Protein
domains
InterPro ID Description
IPR001304 C-type lectin
IPR002353 Type II antifreeze protein
IPR016186 C-type lectin-like
IPR016187 C-type lectin fold
IPR018378 C-type lectin, conserved site
Graphical View of Protein Domain Structure
References
(Earliest) J:65060 Kawai J et al., "Functional annotation of a full-length mouse cDNA collection." Nature 2001 Feb 8;409(6821):685-90
(Latest) J:153503 Tanne A et al., "A murine DC-SIGN homologue contributes to early host defense against Mycobacterium tuberculosis." J Exp Med 2009 Sep 28;206(10):2205-20
All references(17)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory