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Disp1 Gene Detail
 Symbol
Name
ID
Disp1
dispatched homolog 1 (Drosophila)
MGI:1916147


Nomenclature History
Synonyms 1190008H24Rik, DispA
Genetic Map
Chromosome 1
101.2 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 2)

Sequence Map
Ensembl ContigView | UCSC Browser | NCBI Map Viewer
Mammalian
homology
human; chimpanzee; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Disp1 ± 2 cM)
Sequences
Representative Sequences Length Strain/Species
transcript NM_026866 RefSeq | MGI Sequence Detail 5030 C57BL/6
polypeptide Q3TDN0 UniProt | EBI | MGI Sequence Detail 1521 Not Applicable
For the selected sequences
All sequences(27)
Alleles
and
phenotypes
All alleles(6) : Targeted, knock-out(4) Targeted, other(1) Chemically induced(1)
Homozygotes for targeted and chemically induced mutations exhibit a dorsalized neural tube, impaired heart looping, pericardial edema, large forelimbs, and abnormal head shape.
Associated Human Diseases (1)   Alleles Annotated to Human Diseases (2)  
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process determination of left/right symmetry, dorsal/ventral pattern formation...
Component integral to membrane, membrane...
Function hedgehog receptor activity, peptide transporter activity...
External Resources: FuncBase
Expression Literature Summary: (6 records)
Data Summary: Assays (1)    Results (12)    Tissues (4)    Images (4)
Theiler Stages: 21,22
  Assay Type Assays   Results
      RNA in situ 1   12
cDNA source data(38)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents
All nucleic(39) cDNA(38) Other(1)
Microarray probesets(2)
Other database
links
DoTS DT.101387519, DT.40135624, DT.40144994
UniGene 358721
DFCI TC1578610, TC1652175, TC1660213
NIA Mouse Gene Index U040488
Entrez Gene 68897
International Mouse Knockout Project Status Disp1
Protein
domains
InterPro ID Description
IPR000731 Sterol-sensing 5TM box
IPR003392 Patched
IPR004869 MMPL
Graphical View of Protein Domain Structure
References
(Earliest) J:65060 Kawai J et al., "Functional annotation of a full-length mouse cDNA collection." Nature 2001 Feb 8;409(6821):685-90
(Latest) J:142800 Brunskill EW et al., "Atlas of gene expression in the developing kidney at microanatomic resolution. (Erratum: Dev Cell 2009; 16:482)" Dev Cell 2008 Nov;15(5):781-91
All references(14)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/06/2010
MGI_4.32
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