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Sostdc1 Gene Detail
 Symbol
Name
ID
Sostdc1
sclerostin domain containing 1
MGI:1913292

Nomenclature History
Synonyms ectodin, Sostl, USAG-1, Wise
Genetic Map
Chromosome 12
cytoband B2
 
Mapping data( 2)
Sequence Map
Chr12:37040823-37044311 bp, + strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
TreeFam: TF353019
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000036169 Ensembl Gene Model | MGI Sequence Detail 3489 C57BL/6J ± Kb
transcript NM_025312 RefSeq | MGI Sequence Detail 1751 C57BL/6
polypeptide Q9CQN4 UniProt | EBI | MGI Sequence Detail 206 Not Applicable
For the selected sequences
All sequences(22)
Alleles
and
phenotypes 		All alleles(5) : Targeted, knock-out(2) Targeted, other(2) Spontaneous(1)
Polymorphisms SNPs within 2kb(56 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(9)
Process negative regulation of BMP signaling pathway, odontogenesis of dentine-containing tooth...
Component extracellular region, extracellular space...
Function protein binding
External Resources: MouseFunc
Expression Literature Summary: (20 records)
Data Summary: Assays (6)    Results (70)    Tissues (35)    Images (6)
Theiler Stages: 5,8,9,11,13,18,20,21,22,28
  Assay Type Assays   Results
      RT-PCR 4   67
      RNA in situ 2   3
cDNA source data(29)
External Resources: Allen Brain Atlas  GENSAT  GEO 
Molecular
reagents 		All nucleic(33) cDNA(30) Primer pair(3)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000036169
DoTS DT.110932542, DT.40143595
UniGene 43375
DFCI TC1579772
NIA Mouse Gene Index U013871
Entrez Gene 66042
International Mouse Knockout Project Status Sostdc1
Protein
domains
InterPro ID Description
IPR006207 Cystine knot, C-terminal
IPR008835 Sclerostin
Graphical View of Protein Domain Structure
References
(Earliest) J:65060 Kawai J et al., "Functional annotation of a full-length mouse cDNA collection." Nature 2001 Feb 8;409(6821):685-90
(Latest) J:152320 Song L et al., "Lrp6-mediated canonical Wnt signaling is required for lip formation and fusion." Development 2009 Sep;136(18):3161-71
All references(27)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/20/2009
MGI_4.31
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