About   Help   FAQ
Tour our new Quick Search
Clec4e Gene Detail
 Symbol
Name
ID
Clec4e
C-type lectin domain family 4, member e
MGI:1861232

Nomenclature History
Synonyms Clecsf9, Mincle
Genetic Map
Chromosome 6
59.6 cM, cytoband F3
Detailed Genetic Map ± 1 cM
 
Mapping data( 3)

Sequence Map
Chr6:123231807-123239889 bp, - strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Clec4e ± 2 cM)
TreeFam: TF333341
Sequences
Representative Sequences Length Strain/Species Flank
genomic 56619 NCBI Gene Model | MGI Sequence Detail 8083 C57BL/6J ± Kb
transcript NM_019948 RefSeq | MGI Sequence Detail 2519 C57BL/6
polypeptide Q9R0Q8 UniProt | EBI | MGI Sequence Detail 214 Not Applicable
For the selected sequences
All sequences(33)
Alleles
and
phenotypes 		All alleles(2) : Targeted, knock-out(1) Targeted, other(1)
Polymorphisms RFLP(1) SNPs within 2kb(72 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(6)
Process immune response
Component integral to membrane, membrane...
Function binding, sugar binding...
External Resources: MouseFunc
Expression cDNA source data(18)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents 		All nucleic(18) cDNA(18)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000030142
DoTS DT.101329663, DT.101393681, DT.110491022, DT.99854281
UniGene 248327
DFCI TC1574606, TC1610725, TC1637713
NIA Mouse Gene Index U027833
Entrez Gene 56619
International Mouse Knockout Project Status Clec4e
Protein
domains
InterPro ID Description
IPR001304 C-type lectin
IPR002353 Type II antifreeze protein
IPR016186 C-type lectin-like
IPR016187 C-type lectin fold
IPR018378 C-type lectin, conserved site
Graphical View of Protein Domain Structure
References
(Earliest) J:63533 Matsumoto M et al., "A novel LPS-inducible C-type lectin is a transcriptional target of NF-IL6 in macrophages." J Immunol 1999 Nov 1;163(9):5039-48
(Latest) J:136334 Wells CA et al., "The macrophage-inducible C-type lectin, mincle, is an essential component of the innate immune response to Candida albicans." J Immunol 2008 Jun 1;180(11):7404-13
All references(6)
Other
accession IDs 		MGI:2141778
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
11/20/2009
MGI_4.31
Web browser compatibility 		The Jackson Laboratory