Symbol
Name
ID
|
|
|
Synonyms
|
Atpa-1
|
|
Genetic Map
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(123)
|
Alleles
and
phenotypes
|
All alleles(15) :
Targeted, knock-out(1)
Targeted, other(1)
Gene trapped(13)
| Mice homozygous for disruptions in this gene have a lethal phenotype. Heterozygotes display increased anxiety and decreased exploratory behavior in a new environment. |
|
|
Polymorphisms
|
RFLP(3)
SNPs within 2kb(147 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (22 records)
Data Summary:
Assays (10)
Results (53)
Tissues (21)
Images (4)
Theiler Stages: 3,4,5,24,25,26,28
| |
Assay Type |
Assays |
|
Results |
| |
Western blot |
5 |
|
19 |
| |
Immunohistochemistry |
1 |
|
6 |
| |
Northern blot |
4 |
|
28 |
cDNA source data(735)
External Resources:
Allen Brain Atlas
GEO
|
Molecular
reagents
|
All nucleic(745)
Genomic(4)
cDNA(741)
Antibodies(3)
Microarray probesets(3)
|
Other database
links
|
| EC |
3.6.1.37, 3.6.3.9 |
| Ensembl Gene Model |
ENSMUSG00000033161 |
| DoTS |
DT.101183734, DT.101239863, DT.101368510, DT.496244, DT.94145409, DT.94146579, DT.94202066, DT.99872006 |
| UniGene |
280103 |
| DFCI |
TC1573729, TC1706001, TC1751293 |
| NIA Mouse Gene Index |
U024436 |
| Entrez Gene |
11928 |
| VEGA Gene Model |
OTTMUSG00000016447 |
| International Mouse Knockout Project Status |
Atp1a1 |
|
Protein
domains
|
| InterPro ID |
Description |
| IPR001757 |
ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter |
| IPR004014 |
ATPase, P-type cation-transporter, N-terminal |
| IPR005775 |
ATPase, P-type cation exchange, alpha subunit, eukaryotic |
| IPR005834 |
Haloacid dehalogenase-like hydrolase |
| IPR006068 |
ATPase, P-type cation-transporter, C-terminal |
| IPR006069 |
ATPase, P-type cation exchange, alpha subunit |
| IPR008250 |
ATPase, P-type, ATPase-associated domain |
| IPR018303 |
ATPase, P-type phosphorylation site |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:7397
Levenson R et al.,
"Molecular cloning of the mouse ouabain-resistance gene."
Proc Natl Acad Sci U S A 1984 Mar;81(5):1489-93
(Latest)
J:152098
Han F et al.,
"Extracellular potassium dependence of the Na+-K+-ATPase in cardiac myocytes: isoform specificity and effect of phospholemman."
Am J Physiol Cell Physiol 2009 Sep;297(3):C699-705
|
All references(64)
|
Other
accession IDs
|
MGD-MRK-1457, MGD-MRK-1470, MGI:2387620
|
