Symbol
Name
ID
|
|
|
Synonyms
|
gal-9, galectin-9
|
|
Genetic Map
|
|
Chromosome 11
|
Syntenic
|
|
|
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Mapping data(
1)
|
|
|
|
Sequence Map
|
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Mammalian
homology
|
|
|
Sequences
|
All sequences(29)
|
Alleles
and
phenotypes
|
All alleles(13) :
Targeted, knock-out(1)
Gene trapped(12)
| Mice homozygous for a null allele exhibit increased susceptibility to collagen-induced arthritis, increased T-helper 1 cells and decreased regulatory T cells. |
|
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Polymorphisms
|
SNPs within 2kb(26 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (2 records)
Data Summary:
Assays (8)
Results (93)
Tissues (37)
Images (31)
Theiler Stages: 21,25,28
| |
Assay Type |
Assays |
|
Results |
| |
Western blot |
1 |
|
3 |
| |
RT-PCR |
1 |
|
13 |
| |
RNA in situ |
1 |
|
19 |
| |
Immunohistochemistry |
1 |
|
19 |
| |
Northern blot |
4 |
|
39 |
cDNA source data(148)
External Resources:
Allen Brain Atlas
GENSAT
GEO
|
Molecular
reagents
|
All nucleic(152)
Genomic(2)
cDNA(148)
Primer pair(2)
Antibodies(1)
Microarray probesets(2)
|
Other database
links
|
|
Protein
domains
|
| InterPro ID |
Description |
| IPR001079 |
Galectin, carbohydrate recognition domain |
| IPR008985 |
Concanavalin A-like lectin/glucanase |
| IPR013320 |
Concanavalin A-like lectin/glucanase, subgroup |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:38801
Wada J et al.,
"Identification and characterization of galectin-9, a novel beta-galactoside-binding mammalian lectin."
J Biol Chem 1997 Feb 28;272(9):6078-86
(Latest)
J:132889
Seki M et al.,
"Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis."
Clin Immunol 2008 Apr;127(1):78-88
|
All references(9)
|
Other
accession IDs
|
MGD-MRK-39495, MGI:2143968, MGI:2144080, MGI:2144105
|
