Symbol
Name
ID
|
|
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Synonyms
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gal-9, galectin-9, LGALS35, Lgals5
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Genetic Map
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Sequence Map
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Mammalian
homology
|
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Sequences
|
All sequences(29)
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Alleles
and
phenotypes
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All alleles(13) :
Targeted, knock-out(1)
Gene trapped(12)
| Mice homozygous for a null allele exhibit increased susceptibility to collagen-induced arthritis, increased T-helper 1 cells and decreased regulatory T cells. |
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Polymorphisms
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RFLP(1)
SNPs within 2kb(26 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
|
Literature Summary: (3 records)
Data Summary:
Assays (8)
Results (93)
Tissues (37)
Images (31)
Theiler Stages: 21,25,28
| |
Assay Type |
Assays |
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Results |
| |
Western blot |
1 |
|
3 |
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RT-PCR |
1 |
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13 |
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RNA in situ |
1 |
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19 |
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Immunohistochemistry |
1 |
|
19 |
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Northern blot |
4 |
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39 |
cDNA source data(148)
External Resources:
Allen Brain Atlas
GENSAT
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(153)
Genomic(2)
cDNA(149)
Primer pair(2)
Antibodies(1)
Microarray probesets(2)
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Other database
links
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Protein
domains
|
| InterPro ID |
Description |
| IPR001079 |
Galectin, carbohydrate recognition domain |
| IPR008985 |
Concanavalin A-like lectin/glucanase |
| IPR013320 |
Concanavalin A-like lectin/glucanase, subgroup |
Graphical View
of Protein Domain Structure
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References
|
(Earliest)
J:24467
Gitt MA et al.,
"Sequence and mapping of galectin-5, a beta-galactoside-binding lectin, found in rat erythrocytes."
J Biol Chem 1995 Mar 10;270(10):5032-8
(Latest)
J:132889
Seki M et al.,
"Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis."
Clin Immunol 2008 Apr;127(1):78-88
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All references(17)
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Other
accession IDs
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MGD-MRK-24103, MGD-MRK-39495, MGI:103231, MGI:2143968, MGI:2144080, MGI:2144105
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Analysis Tools
MGI BioMart
