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Frat1 Gene Detail
 Symbol
Name
ID
Frat1
frequently rearranged in advanced T-cell lymphomas
MGI:109450


Nomenclature History
Genetic Map
Chromosome 19
37.5 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 6)

Sequence Map
Chr19:41904658-41905299 bp, + strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle    (Mammalian Orthology)
Comparative Map (Mouse/Human Frat1 ± 2 cM)
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000067199 Ensembl Gene Model | MGI Sequence Detail 642 C57BL/6J ± Kb
transcript NM_008043 RefSeq | MGI Sequence Detail 2614 -
polypeptide P70339 UniProt | EBI | MGI Sequence Detail 274 Not Applicable
For the selected sequences
All sequences(15)
Alleles
and
phenotypes
All alleles(1) : Targeted, other(1)
Homozygous mice are healthy and fertile with no obvious abnormalities.
Polymorphisms PCR(1) SNPs within 2kb(7 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Process embryonic axis specification
Component cytoplasm
External Resources: FuncBase
Expression Literature Summary: (4 records)
Data Summary: Assays (6)    Results (79)    Tissues (59)    Images (11)
Theiler Stages: 12,16,19,20,21,22,25,28
  Assay Type Assays   Results
      RT-PCR 2   14
      In situ reporter (knock in) 1   49
      Northern blot 3   16
cDNA source data(15)
External Resources: GENSAT  GEO 
Molecular
reagents
All nucleic(20) Genomic(2) cDNA(15) Primer pair(2) Other(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000067199
DoTS DT.490041
UniGene 4573
DFCI TC1585150
NIA Mouse Gene Index U019456
Entrez Gene 14296
International Mouse Knockout Project Status Frat1
Protein
domains
InterPro ID Description
IPR008014 Glycogen synthase kinase-3 binding protein
Graphical View of Protein Domain Structure
References
(Earliest) J:38606 Jonkers J et al., "Activation of a novel proto-oncogene, Frat1, contributes to progression of mouse T-cell lymphomas." EMBO J 1997 Feb 3;16(3):441-50
(Latest) J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), "The Transcriptional Landscape of the Mammalian Genome" Science 2005;309(5740):1559-1563
All references(12)
Other
accession IDs
MGD-MRK-38495, MGI:2147699

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/06/2010
MGI_4.32
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The Jackson Laboratory