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Fut2 Gene Detail
 Symbol
Name
ID
Fut2
fucosyltransferase 2
MGI:109374


Nomenclature History
Genetic Map
Chromosome 7
23.2 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 4)

Sequence Map
Chr7:52903965-52921678 bp, - strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; gorilla; pig, domestic; rabbit, European; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Fut2 ± 2 cM)
TreeFam: TF315810
Sequences
Representative Sequences Length Strain/Species Flank
genomic 14344 NCBI Gene Model | MGI Sequence Detail 17714 C57BL/6J ± Kb
transcript NM_018876 RefSeq | MGI Sequence Detail 2865 C57BL/6
polypeptide Q9JL27 UniProt | EBI | MGI Sequence Detail 347 Not Applicable
For the selected sequences
All sequences(16)
Alleles
and
phenotypes
All alleles(1) : Targeted, other(1)
Mice homozygous for disruptions in this gene display an essentially normal phenotype. Females are somewhate more susceptible to infections withCandida albicans.
Polymorphisms RFLP(1) SNPs within 2kb(81 from dbSNP Build 128)   SNPs within 2kb including multiple locations(83)
Gene Ontology
(GO)
classifications
All GO classifications(11)
Process carbohydrate metabolic process, protein amino acid glycosylation...
Component Golgi apparatus, integral to membrane...
Function fucosyltransferase activity, galactoside 2-alpha-L-fucosyltransferase activity...
External Resources: MouseFunc
Expression cDNA source data(9)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(10) Genomic(1) cDNA(9)
Microarray probesets(2)
Other database
links
EC 2.4.1.69
Ensembl Gene Model ENSMUSG00000055978
DoTS DT.101297805
UniGene 290046
DFCI TC1584199
NIA Mouse Gene Index U155384
Entrez Gene 14344
International Mouse Knockout Project Status Fut2
Protein
domains
InterPro ID Description
IPR002516 Glycosyl transferase, family 11
Graphical View of Protein Domain Structure
References
(Earliest) J:43607 Domino SE et al., "Molecular cloning, chromosomal assignment and tissue-specific expression of a murine alpha(1,2)fucosyltransferase expressed in thymic and epididymal epithelial cells." Biochem J 1997 Oct 1;327(Pt 1):105-15
(Latest) J:121796 Domino SE et al., "Cell surface fucosylation does not affect development of colon tumors in mice with germline Smad3 mutation." Tumour Biol 2007;28(2):77-83
All references(14)
Other
accession IDs
MGD-MRK-38419

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory