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Adcy9 Gene Detail
 Symbol
Name
ID
Adcy9
adenylate cyclase 9
MGI:108450


Nomenclature History
Synonyms ACtp10, D16Wsu65e, mKIAA0520
Genetic Map
Chromosome 16
2.0 cM, cytoband B1
Detailed Genetic Map ± 1 cM
 
Mapping data( 6)

Sequence Map
Chr16:4287529-4420498 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic    (Mammalian Orthology)
Comparative Map (Mouse/Human Adcy9 ± 2 cM)
TreeFam: TF313845
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000027177 VEGA Gene Model | MGI Sequence Detail 132970 C57BL/6J ± Kb
transcript NM_009624 RefSeq | MGI Sequence Detail 4457 BALB/c
polypeptide P51830 UniProt | EBI | MGI Sequence Detail 1353 Not Applicable
For the selected sequences
All sequences(23)
Alleles
and
phenotypes
All alleles(2) : Gene trapped(2)
Mice homozygous for disruptions in this gene show an increased IgG1 response to ovalbumin challenge.
Polymorphisms SNPs within 2kb(512 from dbSNP Build 128)   SNPs within 2kb including multiple locations(518)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process activation of adenylate cyclase activity, cAMP biosynthetic process...
Component integral to membrane, membrane...
Function adenylate cyclase activity, ATP binding...
External Resources: FuncBase
Expression Literature Summary: (7 records)
Data Summary: Assays (4)    Results (162)    Tissues (126)    Images (19)
Theiler Stages: 11,22,23,28
  Assay Type Assays   Results
      RT-PCR 1   6
      RNA in situ 3   156
cDNA source data(50)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents
All nucleic(53) cDNA(51) Primer pair(1) Other(1)
Microarray probesets(4)
Pathways
cyclic AMP biosynthesis
Other database
links
EC 4.6.1.1
Ensembl Gene Model ENSMUSG00000005580
DoTS DT.110716002, DT.55108410
Consensus CDS Project CCDS27917.1
UniGene 439750
DFCI TC1581343, TC1736968
NIA Mouse Gene Index U036736, U176354
Entrez Gene 11515
VEGA Gene Model OTTMUSG00000027177
International Mouse Knockout Project Status Adcy9
Protein
domains
InterPro ID Description
IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase
IPR018297 Adenylyl cyclase class-3/4/guanylyl cyclase, conserved site
Graphical View of Protein Domain Structure
References
(Earliest) J:28928 Paterson JM et al., "Control of a novel adenylyl cyclase by calcineurin." Biochem Biophys Res Commun 1995 Sep 25;214(3):1000-8
(Latest) J:141439 Kaya F et al., "Ascorbic acid is a regulator of the intracellular cAMP concentration: old molecule, new functions?" FEBS Lett 2008 Oct 29;582(25-26):3614-8
All references(18)
Other
accession IDs
MGD-MRK-33986, MGD-MRK-37494, MGI:106294, MGI:2146626

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/06/2010
MGI_4.32
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The Jackson Laboratory