About   Help   FAQ
Fut7 Gene Detail
 Symbol
Name
ID
Fut7
fucosyltransferase 7
MGI:107692


Nomenclature History
Synonyms FTVII, Fuc-TVII, FucT-VII
Genetic Map
Chromosome 2
Syntenic
 
Mapping data( 1)
Sequence Map
Chr2:25278787-25281894 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: fucosyltransferase
TreeFam: TF316348
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000012106 VEGA Gene Model | MGI Sequence Detail 3108 C57BL/6J ± Kb
transcript NM_013524 RefSeq | MGI Sequence Detail 2185 C57BL/6
polypeptide Q11131 UniProt | EBI | MGI Sequence Detail 389 Not Applicable
For the selected sequences
All sequences(21)
Alleles
and
phenotypes
All alleles(2) : Targeted, knock-out(2)
Mice homozygous for disruptions in this gene are superficially normal. However, abnormalities are found in immune cell function and lymph node morphology. Redeuced tumor metastasis is also seen.
Polymorphisms SNPs within 2kb(24 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process protein amino acid glycosylation
Component Golgi apparatus, integral to membrane...
Function fucosyltransferase activity, transferase activity...
External Resources: FuncBase
Expression cDNA source data(12)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents
All nucleic(16) Genomic(4) cDNA(12)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000036587
DoTS DT.101367179, DT.99855269
Consensus CDS Project CCDS15772.1
UniGene 1203
DFCI TC1586766, TC1675987
NIA Mouse Gene Index U001492
Entrez Gene 14347
VEGA Gene Model OTTMUSG00000012106
International Mouse Knockout Project Status Fut7
Protein
domains
InterPro ID Description
IPR001503 Glycosyl transferase, family 10
Graphical View of Protein Domain Structure
References
(Earliest) J:32202 Smith PL et al., "Expression of the alpha(1,3)fucosyltransferase Fuc-TVII in lymphoid aggregate high endothelial venules correlates with expression of L-selectin ligands." J Biol Chem 1996 Apr 5;271(14):8250-9
(Latest) J:147032 Zhang N et al., "Regulatory T cells sequentially migrate from inflamed tissues to draining lymph nodes to suppress the alloimmune response." Immunity 2009 Mar;30(3):458-69
All references(31)
Other
accession IDs
MGD-MRK-36268, MGI:2139093

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/06/2010
MGI_4.32
Web browser compatibility
The Jackson Laboratory